RT Book, Section A1 Zimmerman, Franklin H. SR Print(0) ID 1200101297 T1 Ventricular Arrhythmias T2 ECG Core Curriculum YR 2023 FD 2023 PB McGraw Hill Education PP New York, NY SN 9780071785211 LK accesscardiology.mhmedical.com/content.aspx?aid=1200101297 RD 2025/01/23 AB A premature depolarization that originates in the ventricular myocardium or terminal Purkinje fibers is termed a ventricular premature complex (VPC). The impulse is initiated outside of the specialized conduction system, activating the nearby myocardium via slow, myocyte-to-myocyte transmission. The impulse then engages the His-Purkinje system to depolarize the remaining myocardium. We know that this type of transmission produces a wide QRS complex (≥0.12 seconds) with secondary T wave abnormalities that are directed opposite to that of the dominant R wave (Figure 19-1).