RT Book, Section A1 Zimmerman, Franklin H. SR Print(0) ID 1200100195 T1 Accessory Pathways and Preexcitation T2 ECG Core Curriculum YR 2023 FD 2023 PB McGraw Hill Education PP New York, NY SN 9780071785211 LK accesscardiology.mhmedical.com/content.aspx?aid=1200100195 RD 2024/04/24 AB In the normal heart a dense band of fibrous tissue forms early in embryogenesis to anatomically and electrically insulate the atria from the ventricles. The only natural electrical link between the atria and the ventricles is via the AV node and His-Purkinje system. Ventricular preexcitation is said to occur when all or part of the ventricular myocardium is activated by the atrial impulse earlier than would be expected if the stimulus were to reach the ventricles by way of the normal AV conduction system. This premature activation can occur only if there is an alternate route that allows the electrical stimulus to bypass the normal physiologic delay of the AV node. Atrioventricular bypass pathways are embryologic remnants of muscle bundles that bridge the heart’s fibrous skeleton, providing the means for abnormal electrical conduction between the atrium and ventricle (Figure 9-1). Transmission of the electrical impulse over such an accessory pathway produces characteristic findings on the ECG and may provide a substrate for cardiac arrhythmias.