RT Book, Section A1 Gallegos, Cesia A1 Young, Bryan D. A1 Miller, Edward J. A2 Heller, Gary V. A2 Hendel, Robert C. SR Print(0) ID 1190157818 T1 18F-FDG PET/CT for Imaging Cardiac Sarcoidosis and Inflammation T2 Nuclear Cardiology: Practical Applications, 4e YR 2022 FD 2022 PB McGraw Hill LLC PP New York, NY SN 9781264257201 LK accesscardiology.mhmedical.com/content.aspx?aid=1190157818 RD 2023/02/07 AB KEY POINTSFluorine-18 fluorodeoxyglucose (18F-FDG) positron emission tomography/computer tomo-graphy (PET/CT) plays a critical role in the diagnosis and treatment assessment of indivi duals with suspected or known cardiac sarcoidosis (CS) and is included in diagnostic algorithms of multisociety guidelinesDiagnosis of active inflammation and assessment of response to treatment are the two primary indications for 18F-FDG PET/CT in CS.Cardiac PET/CT imaging of perfusion and metabolism with 18F-FDG has the potential to risk stratify patients with CS for future cardiac events.Several studies have shown the usefulness of 18F-FDG PET/CT as an additional tool in detecting infections associated with devices and grafts, now incorporated into guidelines for the management of infective endocarditis.18F-FDG PET/CT has high sensitivity to detect infection in challenging causes of cardiac device infections and prosthetic valves, although the specificity may be low, particularly in the early postoperative period.