RT Book, Section
A1 Travin, Mark I.
A1 Valdivia, Ana
A2 Heller, Gary V.
A2 Hendel, Robert C.
SR Print(0)
ID 1190157658
T1 Radionuclide Imaging of Cardiac Innervation
T2 Nuclear Cardiology: Practical Applications, 4e
YR 2022
FD 2022
PB McGraw Hill LLC
PP New York, NY
SN 9781264257201
LK accesscardiology.mhmedical.com/content.aspx?aid=1190157658
RD 2024/04/20
AB KEY  POINTSCardiac  autonomic  imaging  may  play  an  important  role  in  the  management  of  heart  disease,  and  it  can  be  imaged  with  the  norepinephrine  radiotracer  analogue  iodine-123  meta-iodobenzylguanidine  (123I-mIBG)  and  analogous  positron  emission  tomography  (PET)  tracers.Global  and  regional  cardiac  uptake  and  retention  of  123I-mIBG  and  PET  tracers  have  been  robustly  shown  to  effectively  and  independently  risk  stratify  patients  who  have  heart  failure  with  reduced  ejection  fraction  for  occurrence  of  adverse  cardiac  events  including  potentially  lethal  ventricular  arrhythmias.Cardiac  adrenergic  imaging  shows  promise  for  guiding  therapy,  particularly  for  use  of  an  implantable  cardioverter  defibrillator.There  is  potential  to  use  adrenergic  imaging  in  a  multimodality  imaging  protocol  for  improving  the  effectiveness  of  invasive  antiarrhythmic  therapeutic  procedures.