RT Book, Section A1 Gomez, Javier A1 Doukky, Rami A2 Heller, Gary V. A2 Hendel, Robert C. SR Print(0) ID 1190157230 T1 Risk Stratification with Myocardial Perfusion Imaging T2 Nuclear Cardiology: Practical Applications, 4e YR 2022 FD 2022 PB McGraw Hill LLC PP New York, NY SN 9781264257201 LK accesscardiology.mhmedical.com/content.aspx?aid=1190157230 RD 2024/03/28 AB KEY POINTSNormal single-photon emission computed tomography (SPECT) or positron emission tomography (PET) myocardial perfusion imaging (MPI) predicts low risk of major adverse cardiac events.Abnormal SPECT or PET MPI predicts multifold increase in risk, commensurate with severity and extent of perfusion abnormalities.SPECT and PET MPI provide incremental prognostic value beyond clinical, stress, and anatomic data.Ancillary SPECT or PET MPI findings, such as left ventricular ejection fraction, left ventricular function reserve, and transient ischemic dilation, further refine risk prediction.PET-derived myocardial blood flow and coronary flow reserve (CFR) measurements provide valuable prognostic information beyond MPI data and can identify residual risk in patients with normal MPI.SPECT and PET MPI and CFR data can guide management decision making.Coronary artery calcium quantification using hybrid SPECT/CT or PET/CT systems further improves risk prediction.