RT Book, Section A1 Soman, Prem A1 Malhotra, Saurabh A2 Heller, Gary V. A2 Hendel, Robert C. SR Print(0) ID 1190156584 T1 Ventricular Function T2 Nuclear Cardiology: Practical Applications, 4e YR 2022 FD 2022 PB McGraw Hill LLC PP New York, NY SN 9781264257201 LK accesscardiology.mhmedical.com/content.aspx?aid=1190156584 RD 2024/03/28 AB KEY POINTSGated single-photon emission computed tomography (SPECT) is a useful application to distinguish between an artifact due to soft tissue attenuation versus myocardial scar (infarction), and it also improves reader confidence.Determination of left ventricular (LV) function by gated SPECT or radionuclide angiography (RNA) has valuable prognostic value, especially for prediction of death, and this is incremental to perfusion data alone.Gated SPECT may frequently distinguish between ischemia cardiomyopathy and LV dysfunction due to a nonischemic etiology.RNA has excellent reproducibility and permits assessment of both systolic and diastolic functions and is particularly useful in guiding chemotherapy administration.Global dyssychrony may be assessed with gated SPECT and determination of histogram bandwidth and phase standard deviation. These factors may be useful in the prediction of response to resynchronization therapy or development of arrhythmias.