RT Book, Section A1 Manga, Pravin A1 McCutcheon, Keir A1 Tsabedze, Nqoba A2 Fuster, Valentin A2 Narula, Jagat A2 Vaishnava, Prashant A2 Leon, Martin B. A2 Callans, David J. A2 Rumsfeld, John A2 Poppas, Athena SR Print(0) ID 1191381108 T1 Cardiovascular Disease in Patients with HIV T2 Fuster and Hurst's The Heart, 15e YR 2022 FD 2022 PB McGraw-Hill Education PP New York, NY SN 9781264257560 LK accesscardiology.mhmedical.com/content.aspx?aid=1191381108 RD 2023/02/09 AB Chapter SummaryThis chapter focuses on current understanding of the pathogenesis and risk factors associated with heart disease in individuals with human immunodeficiency virus (HIV) infection, and discusses relevant advances in diagnosis and management. Heart disease associated with HIV infection encompasses a broad range of manifestations; infection with HIV may lead to involvement of the pericardium, myocardium, coronary arteries, cardiac valves, pulmonary vasculature, as well as the systemic vasculature (see Fuster and Hurst’s Central Illustration). Depending on the level of viral suppression, patients may present with features of pericardial effusion, cardiomyopathy, ischemic heart disease, diastolic left ventricular dysfunction, pulmonary arterial hypertension, infective endocarditis, and manifestations of thrombotic events in the systemic or venous circulation. The availability of healthcare resources and combined antiretroviral therapy has had a major impact on both the prevalence and severity of cardiovascular disease as well as on short- and long-term outcomes. As many HIV infected persons are living much longer, the role of the cardiovascular specialist is increasingly important in the prevention and management of various cardiac manifestations that may develop in such patients.