RT Book, Section A1 Hayase, Justin A1 Shivkumar, Kalyanam A1 Bradfield, Jason S. A2 Fuster, Valentin A2 Narula, Jagat A2 Vaishnava, Prashant A2 Leon, Martin B. A2 Callans, David J. A2 Rumsfeld, John S. A2 Poppas, Athena SR Print(0) ID 1202447458 T1 Ventricular Arrhythmias and Sudden Cardiac Death T2 Fuster and Hurst's The Heart, 15e YR 2022 FD 2022 PB McGraw-Hill Education PP New York, NY SN 9781264257560 LK accesscardiology.mhmedical.com/content.aspx?aid=1202447458 RD 2024/10/10 AB Chapter SummaryThis chapter discusses the epidemiology and pathophysiology of sudden cardiac death (SCD), which is most often caused by ventricular arrhythmias, and addresses some of the key considerations for the evaluation and treatment of ventricular arrhythmias. Major risk factors for developing these arrhythmias include cardiac structural abnormalities and coronary artery disease (CAD) (see Fuster and Hurst’s Central Illustration). Moreover, a number of inherited channelopathies can predispose to these arrhythmias and should be considered in the context of a structurally normal heart. Ventricular arrhythmias can range from idiopathic premature ventricular complexes, to monomorphic ventricular tachycardia (VT), to ventricular fibrillation (VF). Management of ventricular arrhythmias requires a comprehensive approach that may involve multiple therapies, including an implantable cardioverter defibrillator (ICD), antiarrhythmic medications, catheter ablation, and/or autonomic modulation. The decision-making process for management depends highly upon the presence of underlying structural abnormalities.