RT Book, Section A1 Calnon, Dennis A. A2 Heller, Gary V. A2 Bateman, Timothy M. A2 Case, James A. A2 Arumugam, Parthiban SR Print(0) ID 1159184686 T1 Interpretation of Cardiac PET Myocardial Perfusion Imaging Studies T2 Cardiovascular PET: Current Concepts YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781259860485 LK accesscardiology.mhmedical.com/content.aspx?aid=1159184686 RD 2024/03/29 AB Cardiac positron emission tomographic (PET) myocardial perfusion imaging offers patients and referring health-care providers a superior product with high diagnostic accuracy and risk stratification. As with SPECT, the interpretation of the images is extremely important to the resulting product. Physicians with experience in interpreting single-photon emission computed tomography myocardial perfusion imaging (SPECT MPI) are familiar with the imaging artifacts that reduce confidence in the interpretation of SPECT MPI studies (eg, soft tissue attenuation, gastrointestinal (GI) tracer activity in close proximity to the heart, and patient motion). Interpretation of PET MPI studies requires an understanding of the fundamental differences between PET and SPECT (Table 3-1) and the imaging artifacts unique to PET MPI. As rubidium-82 (82Rb) is the most commonly used radionuclide tracer for PET MPI, the discussion pertains primarily to interpretation of 82Rb PET MPI studies. This chapter examines key aspects to successful interpretation, including differences in interpretation between SPECT and PET, artifacts unique to PET, approaches to interpretation, and, finally, reporting.