RT Book, Section A1 Rozanski, Alan A1 Uretsky, Seth A1 Berman, Daniel S. A2 Heller, Gary V. A2 Bateman, Timothy M. A2 Case, James A. A2 Arumugam, Parthiban SR Print(0) ID 1159184608 T1 Coronary Artery Calcium Scanning in Conjunction with Stress/Rest Myocardial Perfusion Imaging: Complementary Uses for Risk Assessment and Clinical Patient Management T2 Cardiovascular PET: Current Concepts YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781259860485 LK accesscardiology.mhmedical.com/content.aspx?aid=1159184608 RD 2024/04/19 AB Stress/rest myocardial perfusion imaging (MPI) is commonly used for the diagnostic assessment of patients with suspected coronary artery disease (CAD) and for aiding clinical management decisions, such as the need for myocardial revascularization versus medical therapy. The latter use is facilitated by the well-documented relationship between the extent and severity of stress-induced myocardial perfusion abnormalities and the risk for subsequent adverse cardiac events. Despite these utilities, stress/rest MPI imaging has an important limitation: while myocardial perfusion abnormalities are useful for assessing the hemodynamic significance of obstructive coronary stenosis, many patients with normal stress/rest MPI studies have a substantial magnitude of subclinical coronary atherosclerosis, which cannot be detected because they are not flow-limiting in magnitude.1,2 Coronary artery calcium (CAC) scanning is a complementary test that can detect subclinical atherosclerosis.