RT Book, Section A1 Fahmy, Peter A1 Saw, Jacqueline A2 Baliga, R. R. A2 Lilly, Scott M. A2 Abraham, William T. SR Print(0) ID 1160207592 T1 Left Atrial Appendage Closure T2 Color Atlas and Synopsis of Interventional Cardiology YR 2018 FD 2018 PB McGraw-Hill Education PP New York, NY SN 9780071749350 LK accesscardiology.mhmedical.com/content.aspx?aid=1160207592 RD 2024/04/19 AB An 84 year-old woman with hypertension, chronic obstructive pulmonary disease, and chronic renal insufficiency (estimated glomerular filtration, rate 38 mL/min/1.73 m2) also has paroxysmal atrial fibrillation (AF) with a CHADS2 score of 4 and CHA2DS2-VASc score of 6. She suffered a stroke a year ago and was treated with tissue plasminogen activator. This was complicated by hemorrhagic transformation, resulting in expressive dysphagia. Given her history of intracranial hemorrhage, she was deemed to be a poor candidate for long-term oral anticoagulation (OAC) and was thus referred for endovascular left atrial appendage (LAA) closure. Under general anesthesia and transesophageal echocardiography (TEE) guidance, a 28-mm Amplatzer Cardiac Plug (ACP; St. Jude Medical, St. Paul, MN) was successfully deployed. The patient was discharged the following day with no complication and was commenced on dual antiplatelet therapy (aspirin 81 mg/d and clopidogrel 75 mg/d) for 3 months, followed by aspirin indefinitely.