RT Book, Section A1 Sidhu, Sunjeet A1 Chacko, Matthews A2 Baliga, R. R. A2 Lilly, Scott M. A2 Abraham, William T. SR Print(0) ID 1160207116 T1 Transcatheter Aortic Valve Replacement T2 Color Atlas and Synopsis of Interventional Cardiology YR 2018 FD 2018 PB McGraw-Hill Education PP New York, NY SN 9780071749350 LK accesscardiology.mhmedical.com/content.aspx?aid=1160207116 RD 2024/04/17 AB An 88-year-old man with a history of hypertension, insulin-dependent diabetes mellitus, moderate chronic obstructive pulmonary disease, and coronary artery disease with a remote inferior myocardial infarction was recently hospitalized for decompensated heart failure. He reported dyspnea with mild exertion while walking on level ground and associated substernal chest pressure consistent with New York Heart Association class III heart failure. He also reported 2-pillow orthopnea and progressive lower extremity edema. The physical exam demonstrated a grade III/VI late-peaking systolic crescendo-decrescendo murmur with obscuration of the second heart sound. The carotid upstrokes were blunted and delayed. The jugular venous pressure was estimated at 12 cm above the right atrium. A transthoracic echocardiogram demonstrated normal left ventricular function with an ejection fraction of 55% and a calcified trileaflet aortic valve with reduced leaflet mobility. Doppler interrogation of the aortic valve demonstrated a peak systolic velocity of 4.2 m/s and a mean systolic gradient of 45 mm Hg. The aortic valve area, calculated by the continuity equation, was found to be 0.8 cm2. Based on the physical exam and echocardiography findings consistent with severe aortic stenosis, his predicted risk of mortality with surgical aortic valve replacement at 30 days was 11.5%.