RT Book, Section A1 Reich, David L. A1 Mittnacht, Alexander J.C. A1 Kaplan, Joel A. A2 Fuster, Valentin A2 Harrington, Robert A. A2 Narula, Jagat A2 Eapen, Zubin J. SR Print(0) ID 1191188056 T1 ANESTHESIA AND THE PATIENT WITH CARDIOVASCULAR DISEASE T2 Hurst's The Heart, 14e YR 2017 FD 2017 PB McGraw-Hill Education PP New York, NY SN 9780071843249 LK accesscardiology.mhmedical.com/content.aspx?aid=1191188056 RD 2024/04/18 AB SummaryThis chapter discusses anesthesia in patients with cardiovascular disease. Multiple factors must be considered when choosing an anesthetic technique: the patient’s preferences, the requirements of the surgical procedure, and the patient’s underlying medical condition(s) (see accompanying Hurst’s Central Illustration). Almost all general anesthetics have cardiovascular adverse effects and also mask many of the symptoms of cardiovascular decompensation. Moreover, pharmacological reversal of nondepolarizing neuromuscular blocking drugs can lead to arrhythmias in patients with cardiovascular disease and has been associated with cardiac arrest in patients with prior heart transplants. Certain anesthetic techniques, such as neuraxial anesthesia, may be contraindicated in the presence of certain antithrombotic regimens. Spinal anesthesia is contraindicated in patients with severe valvular stenosis or hypertrophic obstructive cardiomyopathy but, with appropriate monitoring, cautious administration of epidural anesthesia may be performed safely in these patients. Inadvertent intravascular injection or absorption of local anesthetics can cause severe arrhythmias, including ventricular fibrillation and cardiovascular collapse. Additionally, epinephrine and phenylephrine may be added in small doses to prolong the duration of action of local anesthetics, but result in slight tachycardia and diastolic hypotension, which is undesirable in patients with certain cardiovascular diseases. With all forms of anesthesia, appropriate monitoring technology must be applied intraoperatively. The anesthesiologist should be prepared to manage hemodynamic alterations and analgesic requirements in the postoperative period.