RT Book, Section A1 Carabello, Blase A. A2 Fuster, Valentin A2 Harrington, Robert A. A2 Narula, Jagat A2 Eapen, Zubin J. SR Print(0) ID 1161731990 T1 MANAGEMENT OF MIXED VALVULAR HEART DISEASE T2 Hurst's The Heart, 14e YR 2017 FD 2017 PB McGraw-Hill Education PP New York, NY SN 9780071843249 LK accesscardiology.mhmedical.com/content.aspx?aid=1161731990 RD 2024/04/20 AB The 2006 American College of Cardiology (ACC)/American Heart Association (AHA) guidelines for the treatment of valvular heart disease (VHD) were notable for the paucity (0.3%) of the recommendations supported by a level of evidence A—that is, evidence supported by two or more randomized controlled trials (RCTs).1 Although several RCTs have been published since then and the evidence level supporting the 2014 guidelines improved markedly,2 there are no RCTs and indeed only limited data-driving management decisions in mixed VHD. In a 230-page document, the current guideline devotes scarcely two pages to the topic. The following chapter will summarize some of the modest data that are available.