RT Book, Section
A1 Johnston-Cox, Hillary
A1 Fuster, Valentin
A1 Kovacic, Jason C.
A2 Fuster, Valentin
A2 Harrington, Robert A.
A2 Narula, Jagat
A2 Eapen, Zubin J.
SR Print(0)
ID 1161723659
T1 BIOLOGY OF THE VESSEL WALL
T2 Hurst's The Heart, 14e
YR 2017
FD 2017
PB McGraw-Hill Education
PP New York, NY
SN 9780071843249
LK accesscardiology.mhmedical.com/content.aspx?aid=1161723659
RD 2024/04/16
AB The  pathogenesis  of  common  cardiovascular  diseases,  including  atherosclerosis  and  hypertension,  involves  diverse  and  complex  pathways.  Significant  advances  in  our  understanding  of  the  underlying  pathobiologies  at  a  molecular  and  cellular  level  are  increasingly  leading  to  the  development  of  new  therapeutic  strategies  targeted  at  primary  etiologies  rather  than  secondary  manifestations  of  vascular  disease.  Thus,  it  is  essential  for  both  inquisitive  scientists  and  clinicians  who  are  taking  care  of  patients  with  cardiovascular  disease  to  understand  the  normal  physiology,  signaling  pathways,  and  function  of  the  different  cell  types  that  constitute  the  layers  of  the  vascular  wall,  in  addition  to  the  complex  interactions  between  the  vasculature,  the  heart  and  the  entire  human  organism  (Fig.  7–1).  This  chapter  will  provide  relevant  basic  knowledge  about  the  underlying  physiology  and  function  of  each  component  of  the  vasculature  and  how  disease  conditions  alter  this  carefully  regulated  system.