RT Book, Section
A1 Abnousi, Freddy
A1 Robinson, Keith A.
A1 Chronos, Nicolas A. F.
A1 Schwartz, Robert S.
A2 Samady, Habib
A2 Fearon, William F.
A2 Yeung, Alan C.
A2 King III, Spencer B.
SR Print(0)
ID 1146606862
T1 Preclinical Laboratory Functions
T2 Interventional Cardiology, 2e
YR 2017
FD 2017
PB McGraw-Hill Education
PP New York, NY
SN 9780071820363
LK accesscardiology.mhmedical.com/content.aspx?aid=1146606862
RD 2024/04/24
AB Although  innovators  brainstorm  ideas  for  novel  therapies  often  while  working  in  the  clinical  setting,  these  ideas  see  the  earliest  translation  into  reality  in  the  preclinical  laboratory.  The  goal  of  the  preclinical  lab  is  to  provide  hands-on  testing  in  the  animal  model  to  guide  focused  revisions  of  a  new  device  or  treatment.  This  is  the  realm  in  which  devices  and  treatments  move  beyond  basic  prototype,  into  early  versions  of  an  eventual  finished  product  for  clinical  use  in  patients.  These  early  versions  get  tested,  revamped,  and  retested,  with  the  goal  of  evaluating  feasibility,  safety,  and  efficacy.  The  preclinical  lab  is  also  a  common  ground  where  interventional  cardiologists,  engineers,  veterinarians,  scientists,  and  industry  can  meet  to  collaborate.