RT Book, Section A1 Pettersson, Gösta B. A1 Hussain, Syed T. A2 Cohn, Lawrence H. A2 Adams, David H. SR Print(0) ID 1144164663 T1 Surgical Treatment of Aortic Valve Endocarditis T2 Cardiac Surgery in the Adult, 5e YR 2017 FD 2017 PB McGraw-Hill Education PP New York, NY SN 9780071844871 LK accesscardiology.mhmedical.com/content.aspx?aid=1144164663 RD 2024/04/16 AB The most common heart valve affected by infective endocarditis (IE) is the aortic valve. Fortunately, significant progress has been made in our understanding and management of aortic valve IE. Clinical manifestations include fever, heart murmur, splenomegaly, embolic events, and bacteremia or fungemia. Early diagnosis is extremely important because progression invariably leads to devastating complications, including acute heart failure, cerebral embolism, and death, if the infection is not treated with antibiotics, surgery, or both. Increasingly, IE has become a “surgical disease,” particularly for aortic valve IE, and during the last decade, more than half of all patients have been operated on during the active phase of the disease (early surgery).1