RT Book, Section
A1 McDonough, Ryan J.
A1 Tcheng, James E.
A2 Samady, Habib
A2 Fearon, William F.
A2 Yeung, Alan C.
A2 King III, Spencer B.
SR Print(0)
ID 1146596660
T1 Thrombolytic Therapy
T2 Interventional Cardiology, 2e
YR 2017
FD 2017
PB McGraw-Hill Education
PP New York, NY
SN 9780071820363
LK accesscardiology.mhmedical.com/content.aspx?aid=1146596660
RD 2023/03/28
AB The  recognition  of  the  proximate  role  of  coronary  thrombosis  secondary  to  plaque  rupture  or  erosion  as  the  underlining  cause  of  ST-segment  elevation  acute  myocardial  infarction  (AMI)  opened  the  door  to  the  development  of  pharmacologic  and  mechanical  interventions  that  have  saved  countless  lives  from  a  disease  process  that  previously  had  few  options  and  carried  a  high  mortality  rate.  Thrombolytic  agents  were  the  first  to  provide  substantial  and  sustained  improvements  in  the  morbidity  and  mortality  of  AMI.  Summarized  in  this  chapter  are  the  key  trials  of  thrombolytic  agents  and  adjuncts  to  fibrinolysis  along  with  recommendations  for  their  application  in  AMI.