RT Book, Section A1 Franco, Veronica A2 Gulati, Martha SR Print(0) ID 1128088238 T1 PULMONARY HYPERTENSION IN WOMEN: GENDER MATTERS T2 Color Atlas and Synopsis of Women's Cardiovascular Health YR 2016 FD 2016 PB McGraw-Hill Education PP New York, NY SN 9780071786201 LK accesscardiology.mhmedical.com/content.aspx?aid=1128088238 RD 2024/04/25 AB Pulmonary arterial hypertension (PAH) is rare and uniformly deadly disease characterized by extensive narrowing of the pulmonary vasculature, leading to progressive increases in pulmonary vascular resistance and ensuing right heart failure.2 The underlying pathogenetic mechanisms of PAH are slowly being unraveled, but to a large degree remain poorly understood. Medial hypertrophy, intimal proliferative and fibrotic changes, perivascular inflammatory infiltrates, and thrombotic lesions are noted in the pulmonary arteries.