RT Book, Section
A1 Waksman, Ron
A2 Dieter, Robert S.
A2 Dieter, Raymond A.
A2 Dieter, Raymond A.
SR Print(0)
ID 1127169149
T1 Peripheral Arterial Brachytherapy
T2 Peripheral Arterial Disease
YR 2009
FD 2009
PB McGraw-Hill Education
PP New York, NY
SN 9780071481793
LK accesscardiology.mhmedical.com/content.aspx?aid=1127169149
RD 2023/03/21
AB With  the  growing  popularity  of  peripheral  vascular  medicine,  identifying  a  reliable  treatment  to  the  plaguing  recurrence  of  restenosis  will  increase  and  augment  the  benefits  of  vascular  intervention.  Investigators  have  shown  that  the  endovascular  delivery  of  radiation  therapy  is  one  such  treatment.  Combating  restenosis  in  the  peripheral  vascular  system  is  contingent  upon  understanding  the  processes,  mechanisms,  and  potential  targets  affected  by  using  brachytherapy.  The  successful  outcome  of  clinical  trials  in  the  coronary  arteries  facilitated  recognition  of  vascular  brachytherapy  (VBT)  to  become  standard  of  care  for  the  treatment  of  in-stent  restenosis  (ISR).  Expansion  of  the  indications  to  de  novo  lesions  identified  the  potential  but  also  limitations  of  the  technology  (late  thrombosis  and  edge  effect).  Simultaneously,  investigators  embarked  on  a  series  of  studies  utilizing  VBT  as  adjunct  therapy  for  intervention  in  peripheral  arteries.