TY - CHAP M1 - Book, Section TI - Antiplatelet Therapy A1 - Mangla, Ashvarya A1 - Gupta, Saurabh A2 - Crawford, Michael H. PY - 2023 T2 - Current Diagnosis & Treatment: Cardiology, 6e AB - Atherosclerosis is a leading cause of cardiovascular disease. Atherosclerotic plaques can acutely rupture, exposing a necrotic core that sets off the coagulation cascade, culminating in vascular occlusion. Activation of platelets is the initial event in this cascade and, depending on the vascular bed involved, can cause acute coronary syndromes, ischemic stroke, mesenteric ischemia, or acute limb ischemia. Antiplatelet therapy forms the core of acute and chronic atherosclerotic disease treatment. In this chapter, we will discuss antiplatelet therapy for the treatment of cardiovascular disease. SN - PB - McGraw Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accesscardiology.mhmedical.com/content.aspx?aid=1198111106 ER -