TY - CHAP M1 - Book, Section TI - Exercise and Pharmacologic Stress Testing A1 - Khalafi, Seyed Mehdi A1 - Ramireddy, Archana A1 - Hendel, Robert C. A2 - Heller, Gary V. A2 - Hendel, Robert C. PY - 2022 T2 - Nuclear Cardiology: Practical Applications, 4e AB - KEY POINTSExercise is the preferred modality for stress testing, whenever possible.Pharmacologic stress myocardial perfusion imaging (MPI) has been well validated when compared to exercise MPI in terms of diagnostic accuracy and risk stratification.Caffeine or aminophylline should be used to reverse adverse effects associated with vasodilator pharmacologic stress.Adjunctive exercise with pharmacologic stress reduces side effects, enhances image quality, and improves the detection of myocardial ischemia.Regadenoson is the most commonly used vasodilator in pharmacologic stress testing, with outstanding clinical value, ease of administration, and reduced side effects.Beta blockers and other antianginal medications should usually be withheld prior to exercise and pharmacologic stress testing. Recent studies, however, have shown that if not feasible to hold beta blockers prior to pharmacologic MPI, testing is still possible with similar results. SN - PB - McGraw Hill LLC CY - New York, NY Y2 - 2024/10/13 UR - accesscardiology.mhmedical.com/content.aspx?aid=1190156246 ER -