TY - CHAP M1 - Book, Section TI - Transcatheter Aortic Valve Replacement A1 - Sidhu, Sunjeet A1 - Chacko, Matthews A2 - Baliga, R. R. A2 - Lilly, Scott M. A2 - Abraham, William T. PY - 2018 T2 - Color Atlas and Synopsis of Interventional Cardiology AB - An 88-year-old man with a history of hypertension, insulin-dependent diabetes mellitus, moderate chronic obstructive pulmonary disease, and coronary artery disease with a remote inferior myocardial infarction was recently hospitalized for decompensated heart failure. He reported dyspnea with mild exertion while walking on level ground and associated substernal chest pressure consistent with New York Heart Association class III heart failure. He also reported 2-pillow orthopnea and progressive lower extremity edema. The physical exam demonstrated a grade III/VI late-peaking systolic crescendo-decrescendo murmur with obscuration of the second heart sound. The carotid upstrokes were blunted and delayed. The jugular venous pressure was estimated at 12 cm above the right atrium. A transthoracic echocardiogram demonstrated normal left ventricular function with an ejection fraction of 55% and a calcified trileaflet aortic valve with reduced leaflet mobility. Doppler interrogation of the aortic valve demonstrated a peak systolic velocity of 4.2 m/s and a mean systolic gradient of 45 mm Hg. The aortic valve area, calculated by the continuity equation, was found to be 0.8 cm2. Based on the physical exam and echocardiography findings consistent with severe aortic stenosis, his predicted risk of mortality with surgical aortic valve replacement at 30 days was 11.5%. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/25 UR - accesscardiology.mhmedical.com/content.aspx?aid=1160207116 ER -