TY - CHAP M1 - Book, Section TI - Balloon-Expandable Transcatheter Aortic Valve Replacement A1 - Gada, Hemal A1 - Kodali, Susheel A2 - Samady, Habib A2 - Fearon, William F. A2 - Yeung, Alan C. A2 - King III, Spencer B. PY - 2017 T2 - Interventional Cardiology, 2e AB - Transcatheter aortic valve replacement (TAVR) has been shown to improve mortality and quality of life in patients with severe aortic stenosis who are designated inoperable or high risk for surgical aortic valve replacement (SAVR).1-5 The first implantation of a transcatheter heart valve (THV) in the aortic position was performed by Cribier et al6 to treat an inoperable patient with severe symptomatic aortic stenosis. From the development of the porcine model to the first clinical implantation in the aortic position, the makeup of a THV was a foldable biological cardiac valve sewn inside an expandable stent frame. This device would be crimped onto a balloon in order to deploy the THV via inflation. With this concept, the technology has emerged as one of the most transformative in the field of interventional cardiology. Given the initial focus on development of a balloon-expandable THV to facilitate TAVR, the largest experiences with TAVR are with balloon-expandable THVs. The main objectives of this chapter are to review the available devices, methods of implantation, clinical outcomes, valve hemodynamics, and durability associated with these systems. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accesscardiology.mhmedical.com/content.aspx?aid=1146603641 ER -