TY - CHAP M1 - Book, Section TI - Nuclear Cardiovascular Imaging in Special Populations A1 - Hendel, Robert C. A1 - Desiderio, Michael C. A1 - Heller, Gary V. A2 - Heller, Gary V. A2 - Hendel, Robert C. Y1 - 2022 N1 - T2 - Nuclear Cardiology: Practical Applications, 4e AB - KEY POINTSThere is abundant literature support for nuclear cardiac imaging in specific populations, with value for both diagnosis and risk stratification.Nuclear cardiac imaging provides important diagnostic and risk stratification data with both single-photon emission computed tomography (SPECT) and positron emission tomography (PET) myocardial perfusion imaging (MPI), while abnormal myocardial blood flow (MBF) assessment identifies microvascular disease with independent risk of coronary events.Data on MBF are increasingly important in specific populations, such as diabetics and women.In diabetic patients, patients with normal exercise SPECT carry a low risk of coronary events, while those with abnormal MBF are at the highest risk of events.Overall, MPI in female patients provides similar diagnostic and risk stratification data in male patients, while MBF data provide further risk stratification especially in nonobstructive disease states.Renal failure patients are at high risk for cardiac events, and myocardial perfusion data provide important risk stratification.In the elderly population, exercise testing alone does not provide adequate discrimination between normal and abnormal results, while SPECT and PET MPI provide incremental prognostic value.In obese patients, the use of attenuation correction, alternate patient positioning, and altered radiopharmaceutical dosing/protocols is recommended, which will then provide similar clinical information to that obtained in a nonobese population. SN - PB - McGraw Hill LLC CY - New York, NY Y2 - 2024/03/29 UR - accesscardiology.mhmedical.com/content.aspx?aid=1190157355 ER -