TY  - CHAP
M1  - Book, Section
TI  - SPECT Myocardial Perfusion Imaging Protocols
A1  - Henzlova, Milena J.
A1  - Hirschfeld, Cole B.
A1  - Einstein, Andrew J.
A2  - Heller, Gary V.
A2  - Hendel, Robert C.
Y1  - 2022
N1  - 
T2  - Nuclear Cardiology: Practical Applications, 4e
AB  - KEY  POINTSSingle-photon  emission  computerized  tomographic  myocardial  perfusion  imaging  (MPI)  is  the  most  common  noninvasive  modality  used  to  evaluate  patients  with  known  or  suspected  coronary  artery  disease  (CAD)  in  the  United  States.Technetium-99m  (Tc-99m)  and  thallium-201  (Tl-201)  distribute  in  the  myocardium  in  proportion  to  regional  blood  flow;  hence,  the  presence  of  a  perfusion  defect  on  imaging  signals  abnormal  myocardial  perfusion.Protocols  involve  rest  and/or  stress  imaging,  using  physical  (e.g.,  treadmill)  or  pharmacological  (e.g.,  vasodilator  or  dobutamine)  stress  agents,  over  1  or  2  days.MPI  is  believed  to  account  for  up  to  20%  of  the  total  patient  radiation  exposure  from  medical  imaging  in  the  United  States  and  thus  efforts  to  reduce  radiation  doses  from  MPI  are  important.Advancements  in  camera  technology  and  post-processing  have  enabled  more  time-efficient  studies  with  better  image  quality  and  lower  administered  radiation  doses.A  normal  stress  study  obviates  the  need  for  subsequent  rest  imaging,  thus  guidelines  now  encourage  the  use  of  stress-first  protocols  to  reduce  radiation  exposure,  reduce  cost,  and  increase  laboratory  efficiency.  
SN  - 
PB  - McGraw Hill LLC
CY  - New York, NY
Y2  - 2024/04/19
UR  - accesscardiology.mhmedical.com/content.aspx?aid=1190156306
ER  -