TY - CHAP M1 - Book, Section TI - Cardiovascular Disease in Patients with HIV A1 - Manga, Pravin A1 - McCutcheon, Keir A1 - Tsabedze, Nqoba A2 - Fuster, Valentin A2 - Narula, Jagat A2 - Vaishnava, Prashant A2 - Leon, Martin B. A2 - Callans, David J. A2 - Rumsfeld, John S. A2 - Poppas, Athena Y1 - 2022 N1 - T2 - Fuster and Hurst's The Heart, 15e AB - Chapter SummaryThis chapter focuses on current understanding of the pathogenesis and risk factors associated with heart disease in individuals with human immunodeficiency virus (HIV) infection, and discusses relevant advances in diagnosis and management. Heart disease associated with HIV infection encompasses a broad range of manifestations; infection with HIV may lead to involvement of the pericardium, myocardium, coronary arteries, cardiac valves, pulmonary vasculature, as well as the systemic vasculature (see Fuster and Hurst’s Central Illustration). Depending on the level of viral suppression, patients may present with features of pericardial effusion, cardiomyopathy, ischemic heart disease, diastolic left ventricular dysfunction, pulmonary arterial hypertension, infective endocarditis, and manifestations of thrombotic events in the systemic or venous circulation. The availability of healthcare resources and combined antiretroviral therapy has had a major impact on both the prevalence and severity of cardiovascular disease as well as on short- and long-term outcomes. As many HIV infected persons are living much longer, the role of the cardiovascular specialist is increasingly important in the prevention and management of various cardiac manifestations that may develop in such patients. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accesscardiology.mhmedical.com/content.aspx?aid=1202453474 ER -