TY  - CHAP
M1  - Book, Section
TI  - THE METABOLIC SYNDROME
A1  - Via, Michael A.
A1  - Mechanick, Jeffrey I.
A2  - Fuster, Valentin
A2  - Harrington, Robert A.
A2  - Narula, Jagat
A2  - Eapen, Zubin J.
Y1  - 2017
N1  - 
T2  - Hurst's The Heart, 14e
AB  - SummaryThis  chapter  discusses  the  pathogenesis,  diagnosis  and  therapeutic  strategies  for  metabolic  syndrome,  which  can  generally  be  defined  as  the  coexistence  of  increased  adiposity/obesity,  hypertension,  dyslipidemia  (high  serum  triglyceride  and/or  low  serum  HDL  levels),  and/or  hyperglycemia/insulin  resistance.  Various  definitions  of  this  syndrome  specify  the  requirement  of  at  least  2-3  of  these  factors,  all  of  which  substantially  increase  the  risk  of  atherosclerotic  disease.  A  large  proportion  of  the  global  adult  population  (20-35%,  depending  on  the  definition  used)  are  thought  to  have  metabolic  syndrome.  Lifestyle,  particularly  sedentary  behaviour,  has  a  dominant  role  in  the  pathogenesis  of  this  syndrome,  but  environmental  and  biological  factors  also  contribute  (see  accompanying  Hurst's  Central  Illustration).  Therapeutic  strategies,  which  should  be  applied  early,  normally  involve  a  combination  of  lifestyle  as  well  as  pharmacological  and/or  procedural  interventions.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/19
UR  - accesscardiology.mhmedical.com/content.aspx?aid=1191186518
ER  -