TY - CHAP M1 - Book, Section TI - THE DIAGNOSIS AND MANAGEMENT OF CARDIOVASCULAR DISEASE IN PATIENTS WITH CANCER A1 - Sahni, Gagan A1 - Scarabelli, Tiziano A1 - Yeh, Edward T.H. A2 - Fuster, Valentin A2 - Harrington, Robert A. A2 - Narula, Jagat A2 - Eapen, Zubin J. Y1 - 2017 N1 - T2 - Hurst's The Heart, 14e AB - SummaryThis chapter discusses the diagnosis and management of cardiovascular disease in patients with cancer. Chemotherapy-induced cardiotoxicity is a growing health issue, in part because the incidence of cancers necessitating aggressive chemotherapy has been increasing, despite the overall incidence of cancer declining since the early 2000s, and also because of increasing longevity of cancer survivors (see accompanying Hurst’s Central Illustration). Radiation therapy can also exert adverse effects on the heart; the pericardium is the cardiac structure most sensitive to irradiation; but the myocardium, heart valves, conduction system, and cardiac vasculature can also be affected. The various acute and chronic cardiovascular complications of cancer therapy include acute coronary syndromes, myocarditis, pericarditis, fluctuations in blood pressure, arrhythmias, thromboembolism, accelerated coronary artery disease, valvulopathy, and heart failure. Many of these conditions can also be cardiovascular manifestations of the cancer itself. Early detection and management of these cardiovascular complications improve patient outcomes. Dedicated cardio-oncology clinics are being established to provide specialized cardiac care to cancer patients. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/10/10 UR - accesscardiology.mhmedical.com/content.aspx?aid=1191188351 ER -