TY - CHAP M1 - Book, Section TI - ACUTE RHEUMATIC FEVER A1 - Zühlke, Liesl A1 - Narula, Jagat A1 - Carapetis, Jonathan R. A2 - Fuster, Valentin A2 - Harrington, Robert A. A2 - Narula, Jagat A2 - Eapen, Zubin J. Y1 - 2017 N1 - T2 - Hurst's The Heart, 14e AB - Acute rheumatic fever (ARF) is a multisystem autoimmune response to untreated or partially treated group A Streptococcus (GAS) pharyngitis. A single severe episode of ARF or recurrent episodes of ARF can result in permanent heart valve damage known as rheumatic heart disease (RHD). Despite a marked decline in ARF and RHD in the developed world, ARF and RHD persist as major public health problems in developing regions of the world, indicative of inadequate access to health care, poorly functioning health systems, and social inequality. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accesscardiology.mhmedical.com/content.aspx?aid=1161731170 ER -