TY - CHAP M1 - Book, Section TI - Peripheral Arterial Brachytherapy A1 - Waksman, Ron A2 - Dieter, Robert S. A2 - Dieter, Raymond A. A2 - Dieter, Raymond A. Y1 - 2009 N1 - T2 - Peripheral Arterial Disease AB - With the growing popularity of peripheral vascular medicine, identifying a reliable treatment to the plaguing recurrence of restenosis will increase and augment the benefits of vascular intervention. Investigators have shown that the endovascular delivery of radiation therapy is one such treatment. Combating restenosis in the peripheral vascular system is contingent upon understanding the processes, mechanisms, and potential targets affected by using brachytherapy. The successful outcome of clinical trials in the coronary arteries facilitated recognition of vascular brachytherapy (VBT) to become standard of care for the treatment of in-stent restenosis (ISR). Expansion of the indications to de novo lesions identified the potential but also limitations of the technology (late thrombosis and edge effect). Simultaneously, investigators embarked on a series of studies utilizing VBT as adjunct therapy for intervention in peripheral arteries. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/25 UR - accesscardiology.mhmedical.com/content.aspx?aid=1127169149 ER -