TY - CHAP M1 - Book, Section TI - ANCA-NEGATIVE SMALL VESSEL VASCULITIS A1 - Bundy, Nicole C. A2 - Dean, Steven M. A2 - Satiani, Bhagwan A2 - Abraham, William T. PY - 2015 T2 - Color Atlas and Synopsis of Vascular Diseases AB - A 39-year-old, previously healthy man presented to rheumatology clinic with 6 days of a progressively severe rash on his lower legs and pain in his knees and ankles. He denied recent upper respiratory or other infection. He took no medications. He was afebrile, and vital signs were normal. Physical examination revealed a rash on the feet and lower legs characterized by palpable purpura with several large areas of confluence (Figure 77-1). His knees were tender, and the ankles were tender and swollen; the remainder of the joint examination was unremarkable. The cardiopulmonary, abdominal, and neurologic examinations were normal. Laboratory values were remarkable for creatinine of 1.4 and a spot urine protein or creatinine ratio of 1.9. Chemistries, including liver functions, and a complete blood count (CBC) were normal. Antineutrophil cytoplasmic antibody (ANCA) studies were negative. A renal biopsy was performed and confirmed a diagnosis of Henoch-Schönlein purpura (HSP) (Figures 77-2 and 77-3). SN - PB - McGraw-Hill Medical CY - New York, NY Y2 - 2024/03/28 UR - accesscardiology.mhmedical.com/content.aspx?aid=1105292326 ER -