TY - CHAP M1 - Book, Section TI - Mitral Regurgitation A1 - Bax, Jeroen J. A1 - Marsan, Nina Ajmone A1 - Bijl, Pieter van der A1 - Treede, Hendrik A1 - DeBonis, Michele A1 - Prendergast, Bernard A1 - Iung, Bernard A1 - Delgado, Victoria A2 - Fuster, Valentin A2 - Narula, Jagat A2 - Vaishnava, Prashant A2 - Leon, Martin B. A2 - Callans, David J. A2 - Rumsfeld, John S. A2 - Poppas, Athena PY - 2022 T2 - Fuster and Hurst's The Heart, 15e AB - Content UpdateMitraClip Continues to Outperform Medical Therapy Alone at 5-years, but Event Rates Remain HighThe COAPT trial investigators randomized 614 patients with heart failure with left ventricular reduced ejection fraction (20-50%) on maximally tolerated guideline-directed medical therapy and symptomatic moderate-to-severe or severe secondary mitral regurgitation to either transcatheter edge-to-edge repair (TEER) with the MitraClip (Abbott) (n = 302) or medical therapy alone (n = 312). Read More SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accesscardiology.mhmedical.com/content.aspx?aid=1202445999 ER -