TY  - CHAP
M1  - Book, Section
TI  - Hypertrophic Cardiomyopathy
A1  - Brahmbhatt, Darshan H.
A1  - Tweed, Katharine
A1  - Williams, Lynne K.
A2  - Baliga, R. R.
A2  - Abraham, William T.
PY  - 2018
T2  - Color Atlas and Synopsis of Heart Failure
AB  - A  17-year-old  adolescent  boy  presented  to  the  general  cardiology  clinic  for  family  screening  after  a  maternal  aunt  had  been  diagnosed  with  hypertrophic  cardiomyopathy  (HCM).  He  had  no  history  of  chest  pain,  breathlessness,  or  syncope.  He  reported  mild  symptoms  of  postural  hypotension.  Examination  revealed  normal  first  and  second  heart  sounds  with  an  audible  and  palpable  fourth  heart  sound,  but  no  murmurs.  His  electrocardiogram  (ECG)  demonstrated  left  ventricular  hypertrophy  (LVH)  with  repolarization  abnormalities,  and  echocardiographic  and  cardiac  magnetic  resonance  imaging  (MRI)  features  of  severe  asymmetric  LVH  are  noted  in  this  patient  (Figure  10-1).  He  had  no  evidence  of  arrhythmia  on  ambulatory  Holter  monitoring,  but  exercise  testing  demonstrated  an  abnormal  blood  pressure  response  on  exercise.  Familial  genetic  testing  was  performed  and  identified  a  pathogenic  mutation  in  the  sarcomere  gene  MYL3.  Given  his  risk  factor  profile  for  sudden  cardiac  death  (SCD),  an  automatic  implantable  cardioverter  defibrillator  (AICD)  was  implanted  for  primary  prevention.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/20
UR  - accesscardiology.mhmedical.com/content.aspx?aid=1161015944
ER  -