TY - CHAP M1 - Book, Section TI - Patient Selection, Procedural Techniques, and Complications of Balloon-Expandable Transcatheter Aortic Valve Replacement A1 - Rahman, Ayaz A1 - Cribier, Alain A1 - Babaliaros, Vasilis A2 - Samady, Habib A2 - Fearon, William F. A2 - Yeung, Alan C. A2 - King III, Spencer B. PY - 2017 T2 - Interventional Cardiology, 2e AB - Aortic stenosis (AS) is the most common acquired valvular disease in adults.1 The incidence of AS has steadily increased along with population life expectancy and age, affecting almost 5% of patients over the age of 75 years.2 The most common cause of valvular AS in adults is calcification of a normal trileaflet valve or a congenital bicuspid valve.3 Severe symptomatic AS has a poor prognosis when treated medically, with a mortality of almost 80% at 2 years.4 Surgical aortic valve replacement (SAVR) is currently the standard of care and accepted to alleviate symptoms and prolong survival; however, up to one-third of patients are denied SAVR because of prohibitive surgical risk (eg, advanced age, significant left ventricular dysfunction).5 SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accesscardiology.mhmedical.com/content.aspx?aid=1146603588 ER -