RT Book, Section
A1 Jacks, Stephanie
A1 Dean, Steven M.
A2 Dean, Steven M.
A2 Satiani, Bhagwan
A2 Abraham, William T.
SR Print(0)
ID 1105293006
T1 PYODERMA GANGRENOSUM
T2 Color Atlas and Synopsis of Vascular Diseases
YR 2015
FD 2015
PB McGraw-Hill Medical
PP New York, NY
SN 9780071749541
LK accesscardiology.mhmedical.com/content.aspx?aid=1105293006
RD 2024/04/19
AB A  35-year-old  woman  with  no  significant  medical  history  presented  with  a  painful  ulcer  on  the  right  pretibial  area.  It  started  as  a  small  pustule  that  subsequently  evolved  into  a  rapidly  enlarging  ulcer  over  the  course  of  several  weeks.  She  may  have  injured  the  area  after  falling  from  her  bicycle  just  prior  to  the  onset  of  the  lesion.  A  comprehensive  review  of  systems  is  notable  for  intermittent  crampy  abdominal  pain  and  diarrhea  for  the  past  year,  which  had  been  attributed  to  irritable  bowel  syndrome.  Laboratory  evaluation  shows  only  a  mild  anemia,  but  biopsy  samples  from  the  terminal  ileum  are  consistent  with  Crohn  disease.  A  skin  biopsy  from  the  edge  of  the  ulcer  itself  is  nondiagnostic.  The  ulcer  improves  after  initiation  of  therapy  with  infliximab  for  her  Crohn  disease.  Pyoderma  gangrenosum  is  suspected.