RT Book, Section
A1 Sahni, Gagan
A1 Scarabelli, Tiziano
A1 Yeh, Edward T.H.
A2 Fuster, Valentin
A2 Harrington, Robert A.
A2 Narula, Jagat
A2 Eapen, Zubin J.
SR Print(0)
ID 1191188351
T1 THE DIAGNOSIS AND MANAGEMENT OF CARDIOVASCULAR DISEASE IN PATIENTS WITH CANCER
T2 Hurst's The Heart, 14e
YR 2017
FD 2017
PB McGraw-Hill Education
PP New York, NY
SN 9780071843249
LK accesscardiology.mhmedical.com/content.aspx?aid=1191188351
RD 2024/04/23
AB SummaryThis  chapter  discusses  the  diagnosis  and  management  of  cardiovascular  disease  in  patients  with  cancer.  Chemotherapy-induced  cardiotoxicity  is  a  growing  health  issue,  in  part  because  the  incidence  of  cancers  necessitating  aggressive  chemotherapy  has  been  increasing,  despite  the  overall  incidence  of  cancer  declining  since  the  early  2000s,  and  also  because  of  increasing  longevity  of  cancer  survivors  (see  accompanying  Hurst’s  Central  Illustration).  Radiation  therapy  can  also  exert  adverse  effects  on  the  heart;  the  pericardium  is  the  cardiac  structure  most  sensitive  to  irradiation;  but  the  myocardium,  heart  valves,  conduction  system,  and  cardiac  vasculature  can  also  be  affected.  The  various  acute  and  chronic  cardiovascular  complications  of  cancer  therapy  include  acute  coronary  syndromes,  myocarditis,  pericarditis,  fluctuations  in  blood  pressure,  arrhythmias,  thromboembolism,  accelerated  coronary  artery  disease,  valvulopathy,  and  heart  failure.  Many  of  these  conditions  can  also  be  cardiovascular  manifestations  of  the  cancer  itself.  Early  detection  and  management  of  these  cardiovascular  complications  improve  patient  outcomes.  Dedicated  cardio-oncology  clinics  are  being  established  to  provide  specialized  cardiac  care  to  cancer  patients.