RT Book, Section A1 Popma, Jeffrey J. A2 Samady, Habib A2 Fearon, William F. A2 Yeung, Alan C. A2 King III, Spencer B. SR Print(0) ID 1146603756 T1 Clinical Outcomes with Self-Expanding Transcatheter Aortic Valve Bioprostheses T2 Interventional Cardiology, 2e YR 2017 FD 2017 PB McGraw-Hill Education PP New York, NY SN 9780071820363 LK accesscardiology.mhmedical.com/content.aspx?aid=1146603756 RD 2024/04/23 AB Since the introduction of the 18-Fr CoreValve self-expanding transcatheter aortic valve replacement (TAVR), over 70,000 implants have been performed worldwide. The use of this self-expanding bioprosthesis has provided an alternative to surgery in patients who are suboptimal for conventional surgical aortic valve replacement and has resulted in improved survival and quality of life for thousands of patients worldwide. There are a number of potential advantages of a self-expanding bioprosthesis over alternative transcatheter designs, including the progressive self-expansion of the inflow frame reducing the degree of paravalvular regurgitation (PVR) over time; supra-annular location of the porcine pericardial valve, which improves hemodynamics and potentially improves long-term durability; and large cell diameter, which provides access to coronary arteries after implantation.