RT Book, Section A1 Rosica, Dillenia A1 Dorbala, Sharmila A2 Heller, Gary V. A2 Hendel, Robert C. SR Print(0) ID 1145444770 T1 Cardiac Amyloid Imaging and 18F-FDG PET/CT for Imaging Sarcoidosis and Cardiovascular Infection T2 Nuclear Cardiology: Practical Applications, 3e YR 2017 FD 2017 PB McGraw-Hill Education PP New York, NY SN 9781259644993 LK accesscardiology.mhmedical.com/content.aspx?aid=1145444770 RD 2024/04/18 AB Cardiac amyloidosis, sarcoidosis, and cardiovascular infections are major causes of morbidity and mortality. Early diagnosis and timely application of specific therapy are critical to improve clinical outcomes.1,2 Echocardiography, cardiac magnetic resonance imaging (CMR), and cardiac CT can detect increased wall thickness, expanded extracellular volume, diffuse late gadolinium enhancement, wall motion abnormalities, fibrosis, vegetations, and abscesses resulting from cardiac amyloidosis, sarcoidosis, or infection. However, by the time the above cardiac structural changes are evident, the disease is at a fairly advanced stage. Moreover, some of these changes are nonspecific and may represent sequelae of other forms of heart diseases and are not disease specific. Radionuclide imaging methods are evolving as specific disease markers in amyloidosis, sarcoidosis, and infection imaging.