RT Book, Section A1 Laredo, James A1 Sidawy, Anton N. A2 Dieter, Robert S. A2 Dieter, Raymond A. A2 Dieter, Raymond A. SR Print(0) ID 1126491673 T1 Lower Extremity Venous Disease T2 Venous and Lymphatic Diseases YR 2011 FD 2011 PB McGraw-Hill Medical PP New York, NY SN 9780071601580 LK accesscardiology.mhmedical.com/content.aspx?aid=1126491673 RD 2024/04/20 AB Lower extremity venous disease is extremely common, with varicose veins remaining the most frequently encountered venous condition followed by chronic venous insufficiency.1,2 The two conditions often occur together, but each condition may also be present clinically without the other. Lower extremity venous disease comprises a clinical spectrum ranging from completely asymptomatic telangiectasias to symptomatic varicose veins to debilitating venous ulcers.1,2 The most frequently encountered symptoms associated with varicose veins include leg swelling, pain, itching, nocturnal cramping, and leg heaviness. Patients with chronic venous insufficiency often present with leg edema, skin hyperpigmentation, stasis dermatitis of the skin involving the ankles, fibrosis of the subcutaneous fat (lipodermatosclerosis), and ulceration.1,2 Lower extremity venous ulceration remains a significant worldwide health problem resulting in significant morbidity.1,2