TY - CHAP M1 - Book, Section TI - Chapter 41. Mitral Valve Repair A1 - Chen, Frederick Y. A1 - Cohn, Lawrence H. A2 - Cohn, Lawrence H. PY - 2012 T2 - Cardiac Surgery in the Adult, 4e AB - Sir Thomas Lauder Brunton, a Scottish physician, first introduced the concept of surgical repair of the mitral valve in 1902.1 Twenty-one years later, Elliot Cutler, the future Moseley Professor of Surgery at the Peter Bent Brigham Hospital in Boston, performed the world's first successful mitral valve operation in 1923 by carrying out a transventricular commissurotomy with a neurosurgical tenotomy knife. A new era in surgery was introduced as well as the reality of mitral valve repair.2 Cutler had worked assiduously on this problem in the Surgical Research Laboratories of Harvard Medical School before turning his attention to a critically ill, bed-bound 12-year-old girl, performing mitral valvulotomy on May 20, 1923. With that seminal operation, the idea of surgically restoring normal anatomy to the pathologic mitral valve came to fruition. Subsequent attempts at transventricular valvulotomy with a cardiovalvutome to produce graded mitral regurgitation resulted in several deaths and Cutler eventually abandoned the procedure.3 Of Cutler's contemporaries, Henry Souttar of England performed a single successful transatrial finger commissurotomy in 1925, but received no further referrals.4 After Souttar there remained little activity in mitral valve repair until Dwight Harken, then the Chief of Cardiothoracic Surgery at the Peter Bent Brigham Hospital, published his groundbreaking series of valvuloplasty patients for mitral stenosis5 concomitantly with Charles Bailey in Philadelphia.6 SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/04/20 UR - accesscardiology.mhmedical.com/content.aspx?aid=55922006 ER -