TY  - CHAP
M1  - Book, Section
TI  - Vulnerable Plaque and the Role of Inflammation in Arterial Disease
A1  - Khadim, Ghazanfar
A1  - Butler, Javed
A1  - Migrino, Raymond Q.
A2  - Dieter, Robert S.
A2  - Dieter, Raymond A.
A2  - Dieter, Raymond A.
PY  - 2009
T2  - Peripheral Arterial Disease
AB  - Atherothrombosis  is  a  systemic  arterial  disease  of  large-  and  medium-sized  arteries  including  the  coronary,  carotid,  aorta,  and  peripheral  arteries.  The  clinical  manifestations  depend  on  the  size  of  the  vessels  and  the  regional  circulation  involved  and  include  coronary  artery  disease,  stroke,  and  peripheral  vascular  disease.  A  paradigm  shift  is  occurring  with  a  change  in  focus  from  the  assessment  and  treatment  of  luminal  narrowing  toward  greater  understanding  of  the  vascular  biology  in  the  arterial  wall  that  leads  to  plaque  vulnerability.  Recent  research  has  shown  that  inflammation  plays  a  key  role  in  the  pathogenesis  and  progression  of  atherothrombosis.  The  basic  concepts  of  evolution  of  atherothrombosis,  and  the  role  of  inflammation  leading  to  vulnerable  plaque,  will  be  discussed  here.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/19
UR  - accesscardiology.mhmedical.com/content.aspx?aid=1127164505
ER  -