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Contributors

Editors

Valentin Fuster, MD, PhD, MACC, FAHA
Richard Gorlin, MD/Heart Research Foundation
Professor of Cardiology
Director, Mount Sinai Heart
Director, The Zena and Michael A. Wiener Cardiovascular Institute and Marie-Josée and Henry R. Kravis Center for Cardiovascular Health
The Mount Sinai Medical Center
New York, New York

Richard A. Walsh, MD, FACC, FAHA
John H. Hord Professor & Chairman
Department of Medicine
Case Western Reserve University
Physician-in-Chief
University Hospitals of Cleveland
Cleveland, Ohio

Robert A. Harrington, MD, FACC, FAHA
Richard Sean Stack, MD Distinguished Professor
Professor of Medicine
Director, Duke Clinical Research Institute
Duke University Medical Center
Durham, North Carolina

Associate Editors

Sharon A. Hunt, MD
Professor of Medicine
Division of Cardiology
Stanford University School of Medicine
Palo Alto, California

Eric N. Prystowsky, MD, FACC, FAHA, FHRS
Consulting Professor of Medicine
Duke University Medical Center
Director, Clinical Electrophysiology Laboratory
St. Vincent Hospital
Indianapolis, Indiana

Spencer B. King III, MD, MACC
President
Saint Joseph's Heart and Vascular Institute
Professor of Medicine Emeritus
Emory University School of Medicine
Atlanta, Georgia

Robert Roberts, MD, FRCP(C), MACC, FAHA
President and CEO
University of Ottawa Heart Institute
Professor of Medicine and Director
The Ruddy Canadian Cardiovascular Genetics Centre
Ottawa, Ontario, Canada

Ira S. Nash, MD, FACC, FAHA, FACP
Chief Medical Officer
Senior Vice President for Medical Affairs
Mount Sinai Medical Center
Associate Professor of Medicine
Associate Professor of Health Policy and Evidence
Mount Sinai School of Medicine
New York, New York

Eric Rose, MD
Edmond A. Guggenheim Professor and Chair, Department of Health Evidence and Policy
Professor, Departments of Medicine (Cardiology), Surgery, Cardiothoracic Surgery
Associate Director for Clinical Outcomes, Mount Sinai Heart
Mount Sinai School of Medicine
New York, New York

Contributors

Jamil A. Aboulhosn, MD
Assistant Professor of Medicine, Co-Director, Ahmanson/UCLA Adult Congenital Heart Disease Center, David Geffen School of Medicine at UCLA, Los Angeles, California
Chapter 84

William T. Abraham, MD, FACP, FACC, FAHA
Professor of Medicine, Physiology, and Cell Biology, Chair of Excellence in Cardiovascular Medicine, Director, Division of Cardiovascular Medicine, Deputy Director, Davis Heart and Lung Research Institute, The Ohio State University, Columbus, Ohio
Chapter 28

David H. Adams, MD
Professor and Chairman, Department of Cardiothoracic Surgery, Marie-Josée and Henry R. Kravis Center, The Mount Sinai School of Medicine, New York, New York
Chapter 77

R. Wayne Alexander, MD, PhD
R. Bruce Logue Professor and Chair, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia
Chapter 8

Suhail Allaqaband, MD, FACC, FCCP, FSCAI
Clinical Associate Professor of Medicine, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Milwaukee Clinical Campus Aurora Cardiovascualr Services, Aurora Sinai/St Luke's Medical Centers, Milwaukee, Wisconsin
Chapter 111

Amit P. Amin, MD
AHA PRT Outcomes Research Fellow, Interventional Cardiology Fellow, Saint Lukes Mid America Heart Institute, University of Missouri, Kansas City, Missouri
Chapter 3

Curtis Anderson, MD
Assistant Professor of Surgery, East Carolina Heart Institute, The Brody School of Medicine at East Carolina University, Greenville, North Carolina
Chapter 98

Dominick J. Angiolillo, MD, PhD
Assistant Professor of Medicine, Director, Cardiovascular Research, University of Florida College of Medicine, Jacksonville, Florida
Chapter 61

Charles Antzelevitch, PhD, FACC, FAHA, FHRS
Masonic Medical Research Laboratory, Utica, New York
Chapter 38

Samuel J. Asirvatham, MD
Professor, Division of Cardiovascular Diseases and Internal Medicine, Division of Pediatric Cardiology, Mayo Clinic College of Medicine, Rochester, Minnesota
Chapter 44

G. Brandon Atkins, MD, PhD, FACC
Assistant Professor, Department of Medicine, Case Western Reserve University School of Medicine, Case Cardiovascular Research Institute, University Hospitals Case Medical Center, Harrington-McLaughlin Heart & Vascular Institute, Cleveland, Ohio
Chapter 70

Usman Baber, MD
Zena and Michael A. Wiener Cardiovascular Institute and Marie-Josée and Henry R. Kravis Center for Cardiovascular Health, Mount Sinai School of Medicine, New York, New York
Chapter 81

Lina Badimon, PhD, FESC, FAHA
Director of the Cardiovascular Research Center, Hospital de la Santa Creu I Sant Pau, Av. Saint Antoni M. Claret, Barcelona, Spain
Chapter 53

Juan Jose Badimon, PhD, FACC, FAHA
Professor of Medicine, Director, Atherothrombosis Research Unit, Cardiovascular Institute, Mount Sanai School of Medicine, New York, New York
Chapter 53

Tanvir Bajwa, MD, FACC, FSCAI
Clinical Professor of Medicine, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Milwaukee Clinical Campus Aurora Cardiovascualr Services, Aurora Sinai/St Luke's Medical Centers, Milwaukee, Wisconsin
Chapter 111

Sameer Bansilal, MD, MS
Fellow, The Zena and Michael A. Weiner, Cardiovascular Institute, Mount Sinai School of Medicine, New York, New York
Chapter 65

Robyn J. Barst, MD
Professor Emerita, Columbia University College of Physicians and Surgeons, New York, New York
Chapter 71

Antoni Bayés de Luna, MD, FESC, FACC
Director of Cardiac Service, Hospital Quiron, Emeritus Professor, Universitat Autónoma de Barcelona, Barcelona, Spain
Chapter 15

Antoni Bayés-Genis, MD, PhD, FESC
Chair, Cardiology Department, Hospital Germans Trias i Pujol, Professor, Department of Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain
Chapter 15

Anton E. Becker, MD, PhD
Professor Emeritus, Department of Cardiovascular Pathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Chapter 37

Suzanne E. Benson, BSc
Clinical Nutritionalist, Department of Nutrition and Dietetics, The Adelaide and Meath Hospital, Dublin Incorporating the National Children's Hospital, Tallaght, Dublin, Ireland
Chapter 67

Daniel S. Berman, MD
Director, Nuclear Cardiology/Cardiac Imaging at Cedars-Sinai Medical Center, Professor of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California
Chapter 21

Gerald J. Berry, MD
Professor of Pathology, Director of Cardiac Pathology, Stanford University Medical Center, Stanford, California
Chapter 29

Courtney L. Bickford, PharmD, BCPS
Pharmacy Clinical Specialist, Cardiology, MD Anderson Cancer Center, Houston, Texas
Chapter 90

Michael J. Blaha, MD, MPH
The John Hopkins Ciccone Center for the Prevention of Heart Disease, Baltimore, Maryland
Chapter 51

Daniel G. Blanchard, MD
Division of Cardiology, University of California School of Medicine, San Diego, California
Chapter 18

Roger S. Blumenthal, MD
Director, Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, Baltimore, Maryland
Chapter 51

Wendy M. Book, MD
Emory Healthcare, Emory University, Atlanta, Georgia
Chapter 94

Kenneth L. Brigham, MD
Associate Vice President and Director of the Predictive Health Institute, Atlanta, Georgia
Chapter 73

Michael R. Bristow, MD, PhD
Professor of Medicine (Cardiology), Co-Director CU Cardiovascular Institute,University of Colorado, Aurora, Colorado
Chapter 32

Craig S. Broberg, MD, FACC
Assistant Professor of Cardiovascular Medicine, Director, Adult Congenital Heart Disease Program, Oregon Health and Science University, Portland, Oregon
Chapter 97

David W. Brown, MD
Assistant Professor in Pediatrics, Harvard Medical School, Boston, Massachusetts
Chapter 83

Dr. Ramon Brugada, MD, PhD, FACC
Director, Medical School, University of Girona, Director, Cardiovascular Genetics Center, Girona, Spain
Chapter 82

Matthew J. Budoff, MD
Associate Professor of Medicine, Division of Cardiology Harbor UCLA Medical Center, David Geffen UCLA School of Medicine, Los Angeles, California
Chapter 22

Hugh Calkins, MD
Professor of Medicine, Johns Hopkins University School of Medicine, Director of Electrophysiology, Johns Hopkins Hospital, Baltimore, Maryland
Chapter 41

Louis R. Caplan, MD
Senior Neurologist, Beth Israel Deaconess Medical Center, Boston, Professor of Neurology, Harvard Medical School, Boston, Massachusetts
Chapter 107

Blasé A. Carabello, MD
Professor, Department of Medicine, Baylor College of Medicine, Houston, Texas
Chapters 77, 78

Jonathan R. Carapetis, MBBS, FRACP, FAFPHM, PhD
Director, Menzies School of Health Research, Professor, Charles Darwin University, Pediatric Infectious Disease Consultant, Royal Darwin Hospital, Darwin, NT, Australia
Chapter 75

Michael P. Carboni, MD
Assistant Clinical Professor, Pediatric Cardiology, Duke Children's Hospital and Health Center, Duke University Medical Center, Durham, North Carolina
Chapter 47

Mark D. Carlson, MD, MA
Chief Medical Officer, Cardiac Rhythm Management Division, St. Jude Medical, Sylmar, California
Chapter 48

Alain Carpentier, MD, PhD
Professor of Cardiothoracic and Vascular Surgery, University of Paris Descartes, Assistance Publique-Hôpitaux de Paris, Hôspital Européen, Paris, France
Chapter 80

Javier G. Castillo
Cardiothoracic Surgery Resident, Department of Cardiothoracic Surgery, The Mount Sinai School of Medicine, New York, New York
Chapter 77

Pamela Charney, MD
Weill Medical College of Cornell University, Professor of Clinical Internal Medicine, Associate Professor of Clinical Obstetrics and Gynecology, New York, New York
Chapter 103

Peng-Sheng Chen, MD
Professor of Medicine, Medtronic Zipes Chair in Cardiology, Director, Krannert Institute of Cardiology, Chief, Division of Cardiology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana
Chapter 38

Joanna Chikwe, MD, FRCS
Assistant Professor, Department of Cardiothoracic Surgery, Mount Sinai Medical Center, New York, New York
Chapter 80

John S. Child, MD
Streisand Professor of Medicine/Cardiology, Director, Ahmanson UCLA Adult Congenital Heart Disease Center, David Geffen School of Medicine at UCLA, Los Angeles, California
Chapter 84

Jayer Chung, MD
Vascular Surgery Fellow, Division of Vascular Surgery and Endovascular Therapy, Emory University Hospital, Atlanta, Georgia
Chapter 110

Michael B. Clark, MD, FACC
Senior Vice-President and Chief Medical Director Swiss Re Life and Health America, Armonk, New York
Chapter 113

Stephen D. Clements, Jr, MD
Professor of Medicine (Cardiology), Emory University School of Medicine, Atlanta, Georgia
Chapter 66

Lynn Clemow, PhD
Assistant Professor, Center for Behavioral Cardiovascular Health, Division of General Medicine, Columbia University—College of Physicians and Surgeons, New York, New York
Chapter 114

Jean-Christophe Cornily, MD
Praticien Hospitalier Universitaire de Cardiologie, Brest University Hospital, Brest, France
Chapter 24

Marco A. Costa, MD, PhD
Professor of Medicine, Director, Invasive Services, Director Center for Research and Innovation, Harrington-McLaughlin Heart & Vascular Institute, University Hospitals Case Medical Center, Cleveland, Ohio
Chapter 20

Rebecca B. Costello, PhD
National Institute of Health, Office of Dietary Supplements, Bethesda, Maryland
Chapter 115

Martin R. Cowie, MD, MSC, FRCP, FESC
Imperial College London, Royal Brompton Hospital, Professor of Cardiology, London, England, United Kingdom
Chapter 27

Monica Kelly Cowles, MD, MS
Assistant Professor, Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, Georgia
Chapter 96

Peter F. Currie, MBChB, MD, FRCPE
Consultant Cardiologist, Clinical Lead for Cardiology, Perth Royal Infirmary, Ninewells Hospital, Tayside Scotland, United Kingdom
Chapter 93

Richard J. Czosek, MD
Assistant Professor, Department of Pediatrics, University of Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio
Chapter 47

Ralph B. D'Agostino, PhD
Professor and Chair, Department of Mathematics and Statistics, Professor of Mathematics, Statistics, and Public Health, Boston University, College of Arts and Sciences, Boston, Massachusetts
Chapter 2

Owais Dar, MBChB, MRCP, MD (RES)
Cardiology Registrat, Royal Brompton and Harefield Hospital, NHS Trust, London, England, United Kingdom
Chapter 27

Melissa A. Daubert, MD
Chief Cardiovascular Fellow, PGY6, Stony Brook Medical Center, Stony Brook, New York
Chapter 22

Karina W. Davidson, PhD
Associate Professor of Medicine & Psychiatry, Columbia Univeristy, Associate Professor, Adjunct Zena & Michael Weiner Cardiovascular Institute, Mount Sinai School of Medicine, New York, New York
Chapter 114

Arjun Deb, MD
Assistant Professor of Medicine (Cardiology) and Cell and Molecular Physiology, McAllister Heart Institute and Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina
Chapter 11

James A. de Lemos, MD
J. Fred Schoelkopf Jr, Chair in Cardiology, Coronary Care Unit and Fellowship Director, University of Texas Southwestern Medical Center, Dallas, Texas
Chapter 59

Anthony N. DeMaria, MD
Division of Cardiology, University of California School of Medicine, San Diego, California
Chapter 18

Christophe Depre, MD, PhD
Associate Professor, Department of Cell Biology and Molecular Medicine, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark, New Jersey
Chapter 54

Roberto De Vogli, MPH, PhD
Lecturer, Departmental of Epidemiology and Public Health, London
Chapter 116

Thomas F. Dodson, MD
Professsor of Surgery, Associate Chairman, Program Director, Department of Surgery, Emory University, Atlanta, Georgia
Chapter 110

John S. Douglas, Jr., MD
Professor of Medicine, Director of International Cardiology and Cardiac Cathetertization Laboratory, Emory University School of Medicine, Atlanta, Georgia
Chapters 62, 64

Helmut Drexler, MD†
Head, Department of Cardiology and Angiology, Medizinische Hochschule Hannover, Hannover, Germany
Chapter 11

Victor Dzau, MD
Chancellor for Health Affairs, Professor of Medicine, Duke University, Durham, North Carolina
Chapter 11

Kim A. Eagle, MD
Albion Walter Hewlett Professor of Internal Medicine, Chief of Clinical Cardiology, Director, Cardiovascular Center, Ann Arbor, Michigan
Chapter 87

William D. Edwards, MD
Consultant in Anatomic Pathology, Department of Laboratory Medicine and Pathology, Professor of Pathology, College of Medicine, Mayo Clinic, Rochester, Minnesota
Chapter 4

John A. Elefteriades, MD
Professor and Chief, Section of Cardiac Surgery, Yale University School of Medicine, New Haven Hospital, New Haven, Connecticut
Chapter 106

Kenneth A. Ellenbogen, MD
Vice Chair, Division of Cardiology, Virginia Commonwealth University School of Medicine, Richmond, Virginia
Chapter 43

N. A. Mark Estes III, MD
Professor of Medicine, Tufts University School of Medicine, Director Cardiac Arrhythmia Center, Tufts Medical Center, Boston, Massachusetts
Chapter 101

Michael S. Ewer, MD, JD
Professor of Medicine, The University of Texas, MD Anderson Cancer Center, Houston, Texas
Chapter 90

Gordon A. Ewy, MD
Professor and Chief Cardiology Director, Sarver Heart Center, University of Arizona College of Medicine, Tucson, Arizona
Chapter 50

Erling Falk, MD, PhD
Professor, Artherosclerosis Research Unit, Department of Cardiology and Institute of Clinical Medicine, Aarhus University Hospital, Skejby, Aarhus N, Denmark
Chapter 52

Noeleen Fallon, MSc
Cardiac Rehabilitation Nurse Manager (CNM II), The Adelaide and Meath Hospital, Dublin Incorporating the National Children's Hospital, Tallaght, Dublin, Ireland
Chapter 67

Michael E. Farkouh, MD, MSc, FACC
Director, Cardiovascular Clinical Trials, University of Toronto, Toronto, Canada, Director, FREEDOM Trial Office, Mount Sinai School of Medicine, New York, New York
Chapters 13, 91

Afshin Farzaneh-Far, MD, PhD
Assistant Consulting Professor of Medicine, Division of Cardiology, Duke University Medical Center, Durham, North Carolina
Chapter 23

Zahi A. Fayad, PhD, FAHA, FACC
Mount Sinai School of Medicine, Professor of Medicine (Cardiology) and Radiology, Director, Translational and Molecular Imaging Institute, New York, New York
Chapter 24

Peter F. Fedullo, MD
Professor of Medicine, University of California San Diego Medical Center, San Diego, California
Chapter 72

T. Bruce Ferguson, Jr., MD
East Carolina Heart Institute, Brody School of Medicine at East Carolina University, Greenville, North Carolina
Chapter 98

Farzan Filsoufi, MD
Billy S. Guyton Distinguished Professor, Professor of Physiology and Medicine, Dean, School of Graduate Studies in the Health Sciences, University of Mississippi Medical Center, Jackson, Mississippi
Chapter 80

Miquel Fiol, MD
Chief, Coronary Care Unit, Son Dureta University Hospital, Palma de Mallorca, Spain
Chapter 15

Gerald F. Fletcher, MD
Professsor in Medicine, Cardiovascular Disease, Mayo Clinic College of Medicine, Mayo Clinic Florida, Jacksonville, Florida
Chapter 100

Thomas R. Flipse, MD
Consultant, Division of Cardiovascular Diseases, Assistant Professor of Medicine, Mayo Clinic, Jacksonville, Florida
Chapter 100

Richard I. Fogel, MD
Clinical Electrophysiologist, St. Vincent Medical Group, Indianapolis, Indiana
Chapter 39

Gary S. Francis, MD
Professor of Medicine, Cardiovascular Disease Division, University of Minnesota, Minneapolis, Minnesota
Chapter 26

Rosario V. Freeman, MD
Associate Professor of Medicine, Division of Cardiology, Director, Echocardiography Laboratory, University of Washington School of Medicine, Seattle, Washington
Chapter 76

William T. Friedewald, MD
Clinical Professor of Public Health (Biostatistics & Epidemiology), Columbia University, Mailman School of Public Health, Clinical Professor of Medicine, College of Physicians & Surgeons, Columbia University, New York, New York
Chapter 113

Victor F. Froelicher, MD
Professor of Medicine, Cardiology Department, Stanford University, Stanford, California
Chapter 16

David R. Fulton, MD
Chief Cardiology Outpatient Services, Department of Cardiology, Children's Hospital Boston, Associate Professor of Pediatrics, Harvard Medical School, Boston, Massachussets
Chapter 83

Valentin Fuster, MD, PhD, MACC, FAHA
Richard Gorlin, MD/Heart Research Foundation, Professor of Cardiology, Director, Mount Sinai Heart, Director, The Zena and Michael A. Wiener Cardiovascular Institute and Marie-Josée and Henry R. Kravis Center for Cardiovascular Health, The Mount Sinai Medical Center, New York, New York
Chapters 13, 24, 52, 53, 56, 81, 91

Mario J. Garcia, MD, FACC, FACP
Chief, Division of Cardiology, Montefiore Medical Center, Professor of Medicine, Albert Einstein College of Medicine, Bronx, New York
Chapter 12

Hector M. Garcia-Garcia, MD, MSc, PhD
Interventional Cardiology Department, Thoraxcenter, Erasmus Medical Center, Rotterdan, The Netherlands
Chapter 20

Guido Germano, PhD, MBA
Professor of Medicine, UCLA School of Medicine, Director, Artifical Intelligence Program, Cedars-Sinai Medical Center, Los Angeles, California
Chapter 21

Bernard J. Gersh, MD, ChB, DPhil
Professor of Medicine, Mayo Medical School, Consultant, Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minnesota
Chapter 60

Gary Gerstenblith, MD
Professor, Department of Medicine, Johns Hopkins University School of Medicine, Johns Hopkins Hospital, Baltimore, Maryland
Chapter 102

Edward M. Gilbert, MD
Professor of Medicine, University of Utah School of Medicine, Salt Lake City, Utah
Chapter 32

Robert C. Gilkeson, MD
Director of Cardiothoracic Imaging, University Hospitals Case Medical Center, Professor, Case Western Reserve University School of Medicine, Cleveland, Ohio
Chapter 17

Gregory R. Giugliano, MD, SM
Associate Director, Cardiac Catheterization Laboratory and Cardiovascular Research, Assistant Professor of Medicine, Tufts University School of Medicine, Baystate Medical Center, Springfield, Massachusetts
Chapter 61

Ty J. Gluckman, MD, FACC
Director, Coronary Care Unit, Provience St. Vincent Heart and Vascular Institute, Portland, Oregon
Chapter 51

Diego Goldwasser, MD
Institut Catala Ciencies Cardiovasculars, Hospital Sant Pau, Barcelona, Spain
Chapter 15

John Gormley, BSc, MA, DPhil
Department of Physiotherapy, School of Medicine, Trinity College, Trinity Centre for the Health Sciences, St. Jame's Hospital, Dublin, Ireland, United Kingdom
Chapter 67

Ian M. Graham, FRCPI, FESC
Professor of Cardiovascular Medicine, Trinity College Dublin, Ireland, Professor of Preventive Cardiology, Royal College of Surgeons in Ireland, Head of Cardiology Department, The Adelaide and Meath Hospital, Dublin Incorporating the National Children's Hospital, Dublin, Ireland
Chapter 67

Joey P. Granger, PhD
Billy S. Guyton Distinguished Professor, Professor of Physiology and Medicine, Dean, School of Graduate Studies in the Health Sciences, University of Mississippi Medical Center, Jackson, Mississippi
Chapter 69

Kathy K. Griendling
Professor of Medicine, Division of Cardiology, Emory University School of Medicine, Atlanta, Georgia
Chapter 8

Garrett J. Gross, PhD
Professor, Department of Pharmacology and Toxicology, Medical College of Wisconsin, Milwaukee, Wisconsin
Chapter 54

Blair P. Grubb, MD
Professor of Medicine and Pediatrics, Health Science Campus, The University of Toledo, Toledo, Ohio
Chapter 48

Scott M. Grundy, MD, PhD
Director, Center for Human Nutrition, UT Southwestern Medical Center at Dallas, Dallas, Texas
Chapter 92

Rory Hachamovitch, MD, MSc
Section of Cardiovascular Imaging, Department of Cardiovascular Medicine, Cleveland, Ohio
Chapter 21

Saptarsi M. Haldar, MD
Assistant Professor of Medicine, Department of Medicine, Harrington-McLaughlin Heart & Vascular Institute, Case Western Reserve University School of Medicine, University Hospitals Case Medical Center, Cleveland, Ohio
Chapters 7, 86

Michael E. Hall, MD
Cardiology Fellow, Department of Medicine, Division of Cardiology, University of Mississippi Medical Center, Jackson, Mississippi
Chapter 69

John E. Hall, PhD
Arthur C. Guyton Professor and Chair, Department of Physiology and Biophysics, Associate Vice Chancellor for Research, University of Mississippi Medical Center, Jackson, Mississippi
Chapter 69

Jonathan L. Halperin, MD
Robert and Harriet Heilbrunn Professor of Medicine (Cardiology), Mount Sinai School of Medicine, Director, Cardiology Clinical Services, The Zena and Michael A. Wiener Cardiovascular Institute, The Marie-Josee and Henry R. Kravis Center for Cardiovascular, New York, New York
Chapter 106

Robert A. Harrington, MD, FACC, FAHA
Richard Sean Stack, MD Distinguished Professor
Professor of Medicine, Director, Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina
Chapters 1, 59

David G. Harrison, MD
Professor, Department of Medicine, Emory University, Atlanta, Georgia
Chapter 8

Ayesha Hasan, MD
Ohio State University Medical Center, Ross Heart Hospital Ohio State University, Columbus, Ohio
Chapter 28

Emily E. Hass, MD
Fellow, Division of Cardiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina
Chapter 60

Takanori Hayasaki, MD, PhD
Research Scholar Division of Cardiology, Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, Michigan
Chapter 58

Sean W. Hayes, MD
Associate Clinical Professor of Medicine, David Geffin School of Medicine, University of California, Assistant Director, Nuclear Cardiology, Cedars-Sinai Medical Center, Los Angeles, California
Chapter 21

Siew Yen Ho, PhD, FRCPath, FESC
Professor of Cardiac Morphology, Head of Cardiac Morphology Unit, Imperial College London, Royal Brompton Hospital, London, England, United Kingdom
Chapter 37

Brian D. Hoit, MD
Professor of Medicine and Physiology and Biophysics, Case Western Reserve Univeristy, Director of Echocardiographic Services, University Hospitals Health Systems, Cleveland, Ohio
Chapters 5, 34, 85

James B. Hoying, PhD
Professor and Chief, Division of Cardiovascular Therapeutics, Cardiovascular Innovation Institute, University of Louisville, Louisville, Kentucky
Chapter 9

Sharon A. Hunt, MD
Professor of Medicine, Division of Cardiology
Stanford University School of Medicine, Palo Alto, California
Chapters 29, 30

Fabien Hyafil, MD, PhD
Assistant Professor, Departments of Cardiology and Nuclear Medicine, Bichat University Hospital, Assistance Publique Hopitaux de Paris, University of Paris Diderot, Paris, France
Chapter 24

Borja Ibanez, MD, PhD
Senior Investigator, Centro Nacional de Investigaciones Cardisvasculares (CNIC) Carlos III, Madrid and Assistant Professor in Cardiology, Hospital Clinico San Carlos, Madrid, Spain
Chapter 53

Shirley Ingram, MSc
Cardiology Nurse Specialist, Department of Cardiac Rehabilitation, The Adelaide and Meath Hospital, Dublin Incorporating the National Children's Hospital, Tallaght, Dublin, Ireland
Chapter 67

Mukesh K. Jain, MD
Ellery Sedgwick Jr Professor of Medicine, University Hospitals Case Medical Center (Clinical), Case Western Reserve University (Academic), Cleveland, Ohio
Chapter 6

M. Fuad Jan, MBBS, MD
Cardiovascular Disease Fellow, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Milwaukee Clinical Campus Aurora Cardiovascular Services, Aurora Sinai/St Luke's Medical Centers, Milwaukee, Wisconsin
Chapter 111

Jooby John, MD, MPH
Chief Fellow, Cardiology, Department of Medicine, The University of Arizona, Tucson, Arizona
Chapter 50

Daniel W. Jones, MD
Chancellor, University of Mississippi, Oxford, Mississippi
Chapter 69

Mark E. Josephson, MD
Professor of Medicine, Harvard Medical School, Director, Harvard-Thorndike Electrophysiology Institute and Arrhythmia Service, Beth Israel Deaconess Medical Center, Boston, Massachusetts
Chapter 49

David L. Joyce, MD
Department of Cardiothoracic Surgery, Stanford University, Palo Alto, Callifornia
Chapter 30

Ronald J. Kanter, MD
Professor, Department of Pediatrics, Division of Pediatric Cardiology, Duke University, Durham, North Carolina
Chapter 47

Samir R. Kapadia, MD
Director Sones Cardiac Catheterization Laboratory, Director Interventional Cardiology Fellowship, Professor of Medicine, Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio
Chapter 108

Joel A. Kaplan, MD
Dean Emeritus, School of Medicine, Former Chancellor, Health Sciences Center, Professor of Clinical Anesthesiology, University of Louisville, Louisville, Kentucky, Professor of Clinical Anesthesiology, University of California, San Diego, San Diego, California
Chapter 88

Mala S. Kaul, MD
Fellow, Division of Rheumatolotgy, Department of Medicine, Duke University Medical Center, Durham, North Carolina
Chapter 89

Bradley B. Keller, MD
Vice Chair for Research, Department of Pediatrics, Kosair Charities Chair and Director, Pediatric Heart Research, Cardiovascular Innovation Institute, Professor of Pediatrics and Bioengineering, Univeristy of Louisville, Louisville, Kentucky
Chapter 9

Richard E. Kerber, MD
Professor of Medicine, Interim Director of Cardiovascular Medicine, University of Iowa Hospitals, Iowa City, Iowa
Chapter 46

Morton J. Kern, MD, FSCAI, FAHA, FACC
Professor of Medicine, Chief Cardiology Long Beach Veterans Administration Hospital, Associate Chief of Cardiology University of California, Irvine, University of California, Irvine Medical Center, Orange, California
Chapter 19

Kerune S. Ketlotgetswe, MD
The John Hopkins Ciccone Center for the Prevention of Heart Disease, Johns Hopkins Hospital, Baltimore, Maryland
Chapter 51

Raymond J. Kim, MD
Associate Professor, Departments of Medicine and Radiology, Co-Director, Duke Cardiovascular Magnetic Resonance Center, Duke University Medical Center, Durham, North Carolina
Chapter 23

Han W. Kim, MD
Assistant Professor of Medicine, Duke Cardiovascular Magnetic Resonance Center, Duke University Health Systems, Durham, North Carolina
Chapter 23

Michael C. Kim, MD, FACC
Professor of Medicine, Coronary Care Unit Mt. Sinai Heart, New York, New York
Chapter 56

Spencer B. King III, MD, MACC
President, Saint Joseph's Heart and Vascular Institute, Professor of Medicine Emeritus, Emory University School of Medicine, Atlanta, Georgia
Chapters 19, 62

Annapoorna S. Kini, MD
Mount Sinai Medical Center, Mount Sinai Hosptial, New York, New York
Chapter 56

Igor Klem, MD
Medical Instructor, Department of Medicine (Cardiology), Duke University Medical Center, Durham, North Carolina
Chapter 23

Timothy K. Knilans, MD
Professor, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati Children's Hospital Medical Center, Director, Clinical Cardiac Electrophysiology and Pacing, Cincinnati, Ohio
Chapter 47

Peter R. Kowey, MD
Professor of Medicine and Clinical Pharmacology, Jefferson Medical College, President, Main Line Heart Center, Lankenau Hospital and Medical Research Center, Wynnewood, Pennsylvania
Chapter 45

Amar Krishnaswamy, MD
Fellow, Division of Cardiology, Cleveland Clinic, Cleveland, Ohio
Chapter 108

Mitchell W. Krucoff, MD
Duke University Medical Center, Duke Clinical Research Institute, Durham, North Carolina
Chapter 115

Michele A. La Merrill, PhD
Environmental Pediatric Fellow, Department of Preventive Medicine, Mount Sinai School of Medicine, New York, New York
Chapter 105

Elena Ladich, MD
CVPath Institute Inc, Gaithersburg, Maryland
Chapter 57

Edward G. Lakatta, MD
Director, Laboratory of Cardiovascular Science, National Institute on Aging Intramural Research Program, National Instiutes of Health, Professor of Physiology, University of Maryland School of Medicine, Professor of Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland
Chapter 102

Philip J. Landrigan, MD, MSc
Ethel H. Wise Professor and Chairman, Department of Preventive Medicine, Professor of Pediatrics, Mount Sinai School of Medicine, New York, New York
Chapter 105

E. Clinton Lawrence, MD
Augustus J. McKelvey Professor of Medicine, Director, Andrew J. McKelvey Lung Transplantation Center, Emory University School of Medicine, Atlanta, Georgia
Chapter 73

Megan C. Leary, MD
Harvard Clinical Research Institute, Boston, Massachusetts
Chapter 107

Tora Leong, MB, MRCPI
Specialist Registrar in Cardiology, Mater Misericordiae University Hospital, Dublin, Ireland, Senior Research Fellow, The Adelaide and Meath Hospital, Dublin Incorporating the National Children's Hospital Tallaght, Dublin, Ireland
Chapter 67

William Lewis, MD
Professor, Department of Pathology & Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia
Chapter 93

Steven L. Liao, MD, FACC
Assistant Professor, Department of Medicine, Assistant Professor, Department of Radiology, The Zena and Michael A. Wiener Cardiovascular Institute, The Mount Sinai School of Medicine, New York, New York, The James J. Peters VA Medical Center, Bronx, New York
Chapter 12

Mark S. Link, MD
Tufts Medical Center, Boston, Massachusetts
Chapter 101

Michael J. Lipinski, MD
Division of Cardiovascular Medicine, University of Virginia Health System, Charlottesville, Virginia
Chapter 16

Brian D. Lowes, MD
Associate Professor, Division of Cardiology, University of Colorado Health Sciences Center, Denver, Colorado
Chapter 32

Bruce W. Lytle, MD
Chairman, Heart and Vascular Institute, Staff, Thoracic and Cardiovascular Surgery, Cleveland Clinic, Cleveland, Ohio
Chapter 65

Vincent Maher, MD, FRCPI, FESC, FACC
Consultant Cardiologist, The Adelaide and Meath Hospital, Dublin Incorporating the National Children's Hospital, Dublin, Ireland
Chapter 67

Joseph F. Malouf, MD, FACC, FAHA
Professor of Medicine, Mayo Clinic College of Medicine, Consultant, Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minnesota
Chapter 4

Hari R. Mallidi, MD
Instructor, Department of Cardiothoracic Surgery, Stanford University, Stanford, California
Chapter 30

Donna M. Mancini, MD
Professor of Medicine, Columbia University, New York, New York
Chapter 35

Ali J. Marian, MD
Professor of Molecular Medicine and Internal Medicine (Cardiology), Director, Center for Cardiovascular Genetics, Institute of Molecular Medicine, Professional Staff, Texas Heart Institute at St. Luke's Episcopal Hospital, The University of Texas Health Science Center, Houston, Texas
Chapter 82

Daniel B. Mark, MD, MPH
Duke University Medical Center, Professor of Medicine, Duke Clinical Research Institute, Director, Outcomes Research, Durham, North Carolina
Chapters 112, 115

Roger R. Markwald, PhD
Distinguished University Professor & Chairman, Department of Regenerative Medicine & Cell Biology, Medical University of South Carolina, Charleston, South Carolina
Chapter 9

Michael Marmot, FRCP
Professor, Department of Epidemiology and Public Health, London, England, United Kingdom
Chapter 116

Barry J. Maron, MD
Director, Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, Minneapolis, Minnesota and Professor of Medicine, Tufts University Medical Center and School of Medicine, Boston, Massashusetts
Chapters 31, 101

Bradley A. Maron, MD
Clinical Follow in Cardiovascular Medicine, Brigham and Women's Hospital, Division of Cardiovascular Medicine, Boston, Massachusetts
Chapter 64

Pedro Martinez-Clark, MD
Assistant Professor of Medicine, Cardiovascular Division, Miller School of Medicine, University of Miami, Miami, Florida
Chapter 63

S. Carolina Masri, MD
Assistant Professor of Medicine,University of Minnesota, Minneapolis, Minnesota
Chapter 104

Tahsin Masud, MD
Associate Professor, Department of Medicine, Emory University School of Medicine, Chief of Nephrology, Emory University Hospital Midtown, Atlanta, Georgia
Chapter 99

Bongavi M. Mayosi, DPhil, FCP(SA)
Department of Medicine, Groote Schuur Hospital and University of Cape Town, Cape Town, South Africa
Chapter 75

John H. McAnulty, MD, FACC, FAHA
Professor Emeritus of Medicine, Division of Cardiology, Oregon Health and Sciences University, Good Samaritan Hospital, Portland, Oregon
Chapter 97

William M. McClellan, MD, MPF
Professor of Medicine and Epidemiology, Renal Division, Department of Medicine, Emory Univeristy School of Medicine and Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia
Chapter 99

William M. McDonald, MD
Professor of Psychiatry and J.B. Fuqua Chair for Late Life Depression, Chief, Division of Geriatric Psychiatry, Atlanta, Georgia
Chapter 96

Elizabeth McNally, MD, PhD
Professor, Department of Medicine, Section of Cardiology, The University of Chicago, Chicago, Illinois
Chapter 10

Reena Mehra, MD, MS
Assistant Professor of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, University Hospitals of Cleveland Case Medical Center, Center of Clinical Investigation, Case School of Medicine, Cleveland, Ohio
Chapter 74

Luisa Mestroni, MD, FACC, FESC, FACP
Professor of Medicine, Director, Molecular Genetics, Cardiovascular Institute, University of Colorado, Aurora, Colorado
Chapter 32

James Metcalfe, MD
Professor of Medicine (Retired), Oregon Health and Science University, Portland, Oregon
Chapter 97

Marc A. Miller, MD
The Zena and Michael A. Wiener Cardiovascular Institute, Mount Sinai School of Medicine, New York, New York
Chapter 73

Maria Mirotsou, PhD
Assistant Professor, Medicine, Duke University, Durham, North Carolina
Chapter 11

Alexander J. C. Mittnacht, MD
Associate Professor, Department of Anesthesiology, The Mount Sinai Medical Center, New York, New York
Chapter 88

Kimberly Morland, PhD, MPH
Mount Sinai School of Medicine, Department of Community and Preventive Medicine, New York, New York
Chapter 105

Douglas C. Morris, MD
J. Willis Hurst Professor of Medicine, Vice Chair for Clinical Affairs, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia
Chapter 66

Debabrata Mukherjee, MD, MS
Professor, Division of Cardiology, Department of Medicine, University of Kentucky, Lexington, Kentucky
Chapter 87

Dominique L. Musselman, MD, MSCR
Emory University School of Medicine, Department of Psychiatry & Behavioral Sciences, Woodruff Research Memorial Building, Atlanta, Georgia
Chapter 96

Samer S. Najjar, MD
Medical Director, Heart Failure and Heart Transplantation, Washington Hospital Center and MedStar Health Research Institute, Washington, DC
Chapter 102

Carlo Napolitano, MD, PhD
Senior Scientist, Molecular Cardiology Labs, IRCCS Fondazione S. Maugeri, Pavia, Italy, Research Associate Professor, Cardiovascular Genetics, New York University School of Medicine, New York, New York
Chapter 36

Ira S. Nash, MD, FACC, FAHA, FACP
Chief Medical Officer, Senior Vice President for Medical Affairs, Mount Sinai Medical Center, Associate Professor of Medicine, Associate Professor of Health Policy and Evidence, Mount Sinai School of Medicine, New York, New York
Chapter 13

Chiadi E. Ndumele, MD
Post Doctoral Fellow, Division of Cardiology and Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, Johns Hopkins University School of Medicine, Baltimore, Maryland
Chapter 51

Charles B. Nemeroff, MD, PhD
Reunette W. Harris Professor, Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, Georgia
Chapter 96

Rick A. Nishimura, MD, FACC
Mayo Clinic College of Medicine, Consultant, Division of Cardiovascular Diseases, Rochester, Minnesota
Chapter 33

Veronica O'Doherty, BA, MPhil, MSc
Head of Psychology Department, The Adelaide and Meath Hospital, Dublin Incorporating the National Children's Hospital, Honorary Lecturer, Department of Clinical Psychology, Trinity College, Dublin, Ireland
Chapter 67

Patrick T. O'Gara, MD
Associate Professor of Medicine, Harvard Medical School, Director, Clinical Cardiology, Brigham and Women's Hospital, Boston, Massachusetts
Chapters 64, 86

Gbenga Ogedegbe, MD, MPH, MS, FAHA
Associate Professor of Medicine, Director of the Center for Healthful Behavior Change, Division of General Internal Medicine, Department of Medicine, New York University School of Medicine, New York, New York
Chapter 68

Gerard O. Oghlakian, MD
Cardiovascular Fellow, Case Western Reserve University, Department of Medicine/Cardiology, Cleveland, Ohio
Chapter 95

Jeffrey W. Olin, DO
Professor of Medicine (Cardiology), Director, Vascular Medicine, Zena and Michael A. Wiener Cardiovascular Institute and Marie-Josee and Henry R. Kravis Center for Cardiovascular Health, Mount Sinai School of Medicine, New York, New York
Chapter 106

Steve R. Ommen, MD
Professor of Medicine, Mayo Clinic, Rochester, Minnesota
Chapter 33

William W. O'Neill, MD
Executive Dean for Clinical Affairs, Chief Medical Officer, University of Miami Health System, Professor of Medicine and Cardiology, University of Miami Miller School of Medicine, Miami, Florida
Chapter 63

Robert O'Rourke, MD, MACP, MACC, FAHA
Professor of Medicine Emeritus, University of Texas Health Science Center at San Antonis, San Antonio, Texas
Chapters 14, 17, 59, 60

Catherine M. Otto, MD
J. Ward Kennedy-Hamilton Professor of Cardiology, Director, Fellowship Programs in Cardiovascular Disease, University of Washington School of Medicine, Seattle, Washington
Chapter 76

Benzy J. Padanilam, MD, FACC
Faculty, Electrophysiology Fellowship Program, Attending Electrophysiologist, St. Vincent Hospital, Indianapolis, Indiana
Chapter 40

Richard L. Page, MD
George R. and Elaine Love Professor, Chair, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconson
Chapter 42

John Pepper, Mchir, FRCS
Professor, Imperial College, School of Medicine, Consultant Cardiac Surgeon, Royal Brompton Hospital, London, England, United Kingdom
Chapter 66

Michael X. Pham, MD, MPH
Clinical Assistant Professor of Medicine, Stanford University School of Medicine, Medical Director of Heart Failure and Transplantation, VA Palo Alto Health Care System, Palo Alto, California
Chapter 29

Thomas G. Pickering, MD, DPhil†
Assistant Professor of Medicine, Center for Behavioral Cardiovascular Health, Columbia Presbyterian Medical Center, New York, New York
Chapter 68

Ileana L. Piña, MD, MPH
Professor of Medicine and Epidemiology/Biostatistics, Case Western Reserve University, Department of Medicine/Cardiology, Cleveland, Ohio
Chapter 95

Sean P. Pinney, MD
Director, Advanced Heart Failure & Cardiac Transplant Program, Associate Professor of Medicine, Mount Sinai School of Medicine, New York, New York
Chapter 35

David J. Pinsky, MD
J. Griswold Ruth & Margery Ruth Professor of Internal Medicine, Professor of Molecular and Integrative Physiology, Taubman Scholar, Chief, Cardiovascular Medicine, Director, Cardiovascular Center, University of Michigan Health System, Ann Arbor, Michigan
Chapter 58

Duane S. Pinto, MD, MPH
Associate Director, Interventional Cardiology Section, Director, Cardiology Fellowship Training Program, Beth Israel Deaconess Medical Center, Assistant Professor, Harvard Medical School, Boston, Massachusetts
Chapter 49

Michael Poon, MD, FACC, FSCCT
Professor of Radiology and Medicine (Cardiology), Director, Advanced Cardiovascular Imaging Program, Department of Radiology, SUNY-Stony Brook School of Medicine, Stony Brook, New York
Chapter 22

Silvia G. Priori, MD, PhD
Associate Professor of Cardiology, Director of Molecular Cardiology, Fondazione Maugeri, University of Pavia, Pavia, Italy, Professor of Medicine, Director of Cardiovascular Genetics, Langone Medical Center, New York University, New York, New York
Chapter 36

Aaron Proweller, MD, PhD
Assistant Professor, Department of Medicine and University Hospitals Harrington-McLaughlin Heart and Vascular Institute, Case Western Reserve University, Cleveland, Ohio
Chapter 6

Eric N. Prystowsky, MD, FACC, FAHA, FHRS
Consulting Professor of Medicine, Duke University Medical Center, Director, Clinical Electrophysiology Laboratory, St. Vincent Hospital, Indianapolis, Indiana
Chapters 39, 40

Mahboob Rahman, MD, MS
Associate Professor Medicine, Case Western Reserve University, University Hospitals Case Medical Center, Louis Stokes Cleveland VA Medical Center, Cleveland, Ohio
Chapter 70

Elliot J. Rayfield, MD
Clinical Professor of Medicine (Endocrinology, Diabetes and Bone Disease), Mount Sinai School of Medicine, New York, New York
Chapter 91

Susan Redline, MD, MPH
Professor, Department of Medicine, Center for Clinical Investigation Case Western Reserve University, Cleveland, Ohio
Chapter 74

Wolfgang G. Rehwald, PhD
Senior Scientist, Cardiovascular MR Research and Development, Siemens Healthcare, Siemens Medical Solutions USA, Inc., Customer Solutions Group, Duke Cardiovascular MR Center, Durham, North Carolina
Chapter 23

David L. Reich, MD
Horace W. Goldsmith Professor and Chair, Department of Anesthesiology, Mount Sinai School of Medicine, New York, New York
Chapter 88

Matthew R. Reynolds, MD, SM
Division of Cardiology, Beth Israel Deaconess Medical Center, Assistant Professor of Medicine, Harvard Medical School, Boston, Massachusetts
Chapter 49

Robert W. Rho, MD
Associate Professsor, University of Washington School of Medicine, Director, Cardiac Electrophysiology Ablation Program, University of Washington Medical Center, Seattle, Washington
Chapter 42

Nina Rieckmann, PhD
Senior Scientist, Berlin School of Public Health, Chanite University Medical Center, Berlin, Germany
Chapter 114

Robert Roberts, MD, FRCP(C), MACC, FAHA
President and CEO, University of Ottawa Heart Institute, Professor of Medicine and Director, The Ruddy Canadian Cardiovascular Genetics Centre, Ottawa, Ontario, Canada
Chapters 10, 82

Thom W. Rooke, MD
Krehbiel Professor of Vascular Medicine, Mayo Clinic, Rochester, Minnesota
Chapter 109

Lewis J. Rubin, MD
Professor of Medicine, University of California, San Diego School of Medicine, La Jolla, California
Chapter 71

James H. F. Rudd, MD, PhD, MRCP(UK)
HEFCE Senior Lecturer and Honorary Consultant, Cardiologist, Division of Cardiovascular Medicine, University of Cambridge, Cambridge, United Kingdom
Chapter 24

Cyril Ruwende, MD, MSc, PhD
General and Interventional Cardiologist, Michigan Heart, PC, Ann Arbor, Michigan
Chapter 58

Joseph F. Sabik III, MD
Chair, Department of Thoracic and Cardiovascular Surgery, Professor of Surgery, The Cleveland Clinic, Cleveland, Ohio
Chapter 65

Robert E. Safford, MD, PhD
Consultant, Division of Cardiovascular Diseases, Barbard Woodward Lips Professor of Medicine, Mayo Clinic, Jacksonville, Florida
Chapter 100

Heinrich R. Schelbert, MD, PhD
Professor, Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, Los Angeles, California
Chapter 25

Steven P. Schulman, MD
Professor of Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Director, Coronary Care Unit, Johns Hopkins University, Baltimore, Maryland
Chapter 102

Patrick W. Serruys, MD, PhD
Professor, Thoraxcentr, Erasmus Medical Center, The Netherlands
Chapter 20

James B. Seward, MD, FACC
Emeritis Consultant, Cardiovascular Diseases, Internal Medicine and Pediatric Cardiology, Nasseff Professor in Cardiology, Professor of Medicine and Pediatrics, Rochester, Minnesota
Chapter 4

Pravin M. Shah, MD, MACC
Chair, Medical Director, Hoag Hospital's Heart and Vascular Institute, Newport Beach, California
Chapter 79

James A. Shaver, MD
Professor of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania
Chapter 14

Leslee J. Shaw, PhD, FASNC, FACC, FAHA
Professor of Medicine, Emory University School of Medicine, Atlanta, Georgia
Chapters 21, 64

Mark E. Silverman, MD, MACP, FRCP, FACC†
Emeritus Professor of Medicine, Emory University, Chief of Cardiology, Fuqua Heart Center of Atanta, Piedmont Hospital, Atlanta, Georgia
Chapter 1

Daniel I. Simon, MD
Chief, Division of Cardiovascular Medicine, Director, Harrington-McLaughlin Heart & Vascular Institute, University Hospitals Case Medical Center, Herman K. Hellerstein Professor of Cardiovascular Research, Case Western Reserve University School of Medicine, Cleveland, Ohio
Chapter 61

Sidney C. Smith, Jr, MD
Professor of Medicine, Center for Cardiovascular Science and Medicine, University of North Carolina School of Medicine, Chapel Hill, North Carolina
Chapter 92

Andrew L. Smith, MD
Associate Professor of Medicine, Division of Cardiology Harbor UCLA Medical Center, David Geffen UCLA School of Medicine, Los Angeles, California
Chapter 94

John A. Spertus, MD, MPH
Clinical Director of Outcomes Research, Saint Luke's Mid America Heart Institute, Professor, University of Missouri-Kansas City, Kansas City, Missouri
Chapter 3

E. William St. Clair, MD
Professor of Medicine and Immunology, Department of Medicine, Division of Rheumatology and Immunology, Duke University Medical Center, Durham, North Carolina
Chapter 89

William G. Stevenson, MD
Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts
Chapter 44

Joseph M. Sweeny, MD
Assistant Professor of Medicine, Cardiac Catheterization Laboratory, Mount Sinai Medical Center/Mount Sinai Heart, New York, New York
Chapter 73

A. Jamil Tajik, MD
Thomas J. Watson Jr Professor, Professor of Medicine and Pediatrics, Chairman Emeritus, Sheikh Zayed Cardiovascular Center, Mayo Clinic, Rochester, Minnesota, Consultant, Cardiovascular Division, Mayo Clinic, Scottsdale, Arizona
Chapters 4, 33

W. H. Wilson Tang, MD
Assistant Professor, Cleveland Clinic Lerner College of Medicine, Heart and Vascular Institute, Cleveland Clinic, Cleveland, Ohio
Chapter 26

Victor F. Tapson, MD
Duke University Medical Center, Durham, North Carolina
Chapter 89

Anne L. Taylor, MD
John Lindenbaum Professor of Medicine, Vice Dean for Academic Affairs, Columbia Univeristy Medical Center, New York, New York
Chapter 104

Usha B. Tedrow, MD, MSc
Director, Clinical Electrophysiology Program, Brigham and Women's Hospital, Boston, Massachusetts
Chapter 44

Gaetano Thiene, MD, FRCP
Professor, Pathological Anatomy, Department of Medico-Diagnostic Sciences and Special Therapies, University of Padua Medical School, Padua, Italy
Chapter 31

Amit J. Thosani, MD
Clinical Fellow in Cardiac Electrophysiology, Beth Israel Deaconess Medical Center, Boston, Massachusetts
Chapter 49

Ramachandran S. Vasan, MD, DM
Professor and Chief, Section of Preventative Medicine and Epidemiology, Department of Medicine, Senior Investigator, The Framingram Heart Study, Boston University, Boston, Massachusetts
Chapter 2

Stephen F. Vatner, MD
University Professor and Chair, Department of Cell Biology and Molecular Medicine, University of Medicine and Denistry of New Jersey, New Jersey Medical School, Newark, New Jersey
Chapter 54

Lakshmi Venkitachalam, MPhil, MPH, PhD
AHA-PRT Outcomes Research Fellow, Saint Luke's Mid America Heart Institute, Kansas City, Missouri
Chapter 3

Pugazhendhi Vijayaraman, MD
Program Director, Cardiac Electrophysiology Fellowship, Geisinger Medical Center, Danville, Pennsylvania
Chapter 43

Renu Virmani, MD
President and Medical Director, CVPath Institute, Inc, Gaithersburg, Maryland
Chapter 57

Scott Visovatti, MD
Division of Cardiology, University of Michigan, Ann Arbor, Michigan
Chapter 58

John H. K. Vogel, MD, MACC, SCAI, ESC
Honorary Faculty, Santa Barbara Cottage Hospital, Staff, North Hawaii Community Hospital, Santa Barbara, California
Chapter 115

Albert L. Waldo, MD
The Walter H. Pritchard Professor of Cardiology, Professor of Medicine, Case Western Reserve University, Divison of Cardiology, Cleveland, Ohio
Chapter 40

Bruce F. Waller, MD
Cardiologist, The Care Group Part of St. Vincent Medical Group, Clinical Professor of Medicine and Pathology, Indiana University School of Medicine, Indianapolis, Indiana
Chapter 55

Richard A. Walsh, MD, FACC, FAHA
John H. Hord Professor & Chairman, Department of Medicine, Case Western Reserve University, Physician-in-Chief, University Hospitals of Cleveland, Cleveland, Ohio
Chapters 5, 6, 7, 14, 26

Paul W. Wennberg, MD
Gonda Vascular Center, Department of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota
Chapter 109

William Whang, MD, MS
Assistant Professor of Clinical Medicine, Division of Cardiology, Columbia University Medical Center, New York, New York
Chapter 114

Charles F. Wooley, MD†
Professor of Medicine Emeritus, Division of Cardiology, Department of Internal Medicine, The Ohio State University, Heart Lung Research Institute, Columbus, Ohio
Chapter 1

Jackson T. Wright, Jr., MD, PhD
Professor of Medicine, Director, Clinical Hypertension Program, Division of Nephrology and Hypertension, Program Director, William T. Dahms Clinical Research Center, Case Western Reserve University, Cleveland, Ohio
Chapter 70

Jay Yadav, MD
Staff Interventional Cardiologist, Piedmont Heart Institute, Atlanta, Georgia
Chapter 108

Gan-Xin Yan, MD, PhD
Main Line Health Heart Center, Lankenau Institute for Medical Research, Wynnewood, Pennsylvania
Chapter 45

Eric H. Yang, MD, FACC
Assistant Professor of Medicine, Director of the Coronary Care Unit, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina
Chapter 60

Saami K. Yazdani, PhD
CBPath Institute, Inc., Gaithersburg, Maryland
Chapter 57

Edward T. H. Yeh, MD
McNair Scholar, Texas Heart Institute, Chairman, Department of Cardiology, The University of Texas MD Anderson Cancer Center, Houston, Texas
Chapter 90

Justin P. Zachariah, MD, MPH
Assistant in Cardiology, Children's Hospital Boston, Instructor of Pediatrics, Harvard Medical Schoool, Boston, Massachusetts
Chapter 2

Deceased

Acknowledgments

The editors and authors would like to acknowledge and thank the following individuals for their contributions to the 12th edition of Hurst's The Heart. Although their work forms part of the chapters of the 13th edition, they are not authoring the current chapters. (Chapter numbers refer to the 13th edition.)
Bruce R. Brodie, MD, Chapter 63; Allen P. Burke, MD, Chapter 57; Jonathan M. Chen, MD, Chapter 29; Harry Crijns, MD, PhD, Chapter 45; Gregory Engel, MD, Chapter 16; Michael D. Faulx, MD, Chapter 95; Gary S. Francis, MD, Chapter 95; Sanjaya Gupta, MD, Chapter 34; Neeru Kaushik, MD, Chapter 9; Daniel J. Lenihan, MD, Chapter 90; Giuseppe Maiolino, MD, Chapter 22; Deepak G. Nair, MD, MS, MHA, RVT, Chapter 110; Keith R. Oken, MD, Chapter 100; Thomas G. Pickering, MD, DPhil, Chapter 114; Philip Poole-Wilson, MD, FRCP, FESC, FACC, FMedSci, Chapters 26 and 28; Vivek Rajagopal, MD, Chapter 108; Arash Rashidi, MD, Chapter 70; Eric A. Rose, MD, Chapter 29; Allen M. Samarel, MD, Chapter 7; John S. Schroeder, MD, Chapter 29; Daichi Shimbo, MD, Chapter 114; Mark E. Silverman, MD, MACP, FRCP, FACC, Chapter 14; Edmund H. Sonnenblick, MD, FACC, Chapter 26; Lisa M. Sullivan, PhD, Chapter 2; Ramachandran S. Vason, MD, DM, FACC, Chapter 2; Andy Wessels, PhD, Chapter 9; James A. White, MD, Chapter 23

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