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Harrison's Cardiovascular Medicine, Second Edition Copyright © 2013 by The McGraw-Hill Companies, Inc. All rights reserved. Printed in China. Except as permitted under the United States Copyright Act of 1976, no part of this publication may be reproduced or distributed in any form or by any means, or stored in a data base or retrieval system, without prior written permission of the publisher.

Dr. Fauci's work as an editor and author was performed outside the scope of his employment as a U.S. government employee. This work represents his personal and professional views and not necessarily those of the U.S. government.

Previous editions copyright © 2013, 2010, 2008 by the McGraw-Hill Companies, Inc.

1 2 3 4 5 6 7 8 9 0 CTP/CTP 18 17 16 15 14 13

ISBN 978-0-07-181498-0

MHID 0-07-181498-1

This book was set in Bembo by Cenveo® Publisher Services. The editors were James F. Shanahan and Kim J. Davis. The production supervisor was Catherine H. Saggese. Project management was provided by Tania Andrabi, Cenveo Publisher Services. The cover design was by Thomas DePierro. Cover illustration, the coronary vessels of the heart, © MedicalRF.com/Corbis.

China Translation & Printing Services, Ltd. was the printer and binder.

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